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Infection of a human hepatoma cell line by hepatitis B virus.
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Andre Guillouzo, Anne Corlu, Caroline Aninat, Denise Glaise, Fabrice Morel, Christiane Guguen-Guillouzo;
The human hepatoma HepaRG cells: a highly differentiated model for studies of liver metabolism and toxicity of xenobiotics.
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Virginie Cerec, Denise Glaise, Delphine Garnier, Serban Morosan, Bruno Turlin, Bernard Drenou, Philippe Gripon, Dina Kremsdorf, Christiane Guguen-Guillouzo, Anne Corlu;
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Hepatology 45:957-967(2007)

Patent=US7456018
Philippe Gripon, Christiane Guguen-Guillouzo, Christian Trepo, Sylvie Rumin;
Human hepatoma lines, methods for obtaining same and uses thereof.
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Steven N. Hart, Ye Li, Kaori Nakamoto, Eva-Anne Subileau, David Steen, Xiao-Bo Zhong;
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Marie-Jeanne Marion, Olivier Hantz, David Durantel;
The HepaRG cell line: biological properties and relevance as a tool for cell biology, drug metabolism, and virology studies.
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Liesbeth Ceelen, Ward De Spiegelaere, Michael David, Jurgen De Craene, Mathieu Vinken, Tamara Vanhaecke, Vera Rogiers;
Critical selection of reliable reference genes for gene expression study in the HepaRG cell line.
Biochem. Pharmacol. 81:1255-1261(2011)

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Tommy B. Andersson, Kajsa P. Kanebratt, J. Gerry Kenna;
The HepaRG cell line: a unique in vitro tool for understanding drug metabolism and toxicology in human.
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Carolina Huaman Samanez, Sandrine Caron, Olivier Briand, Helene Dehondt, Isabelle Duplan, Folkert Kuipers, Nathalie Hennuyer, Veronique Clavey, Bart Staels;
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Arch. Physiol. Biochem. 118:102-111(2012)

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Sebastien Antherieu, Christophe Chesne, Ruo-Ya Li, Christiane Guguen-Guillouzo, Andre Guillouzo;
Optimization of the HepaRG cell model for drug metabolism and toxicity studies.
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Izabela Sokolowska, Cristina M. Dorobantu, Alisa G. Woods, Alina Macovei, Norica Branza-Nichita, Costel C. Darie;
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High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions.
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Rowena L.C. Sison-Young, Dimitra Mitsa, Rosalind E. Jenkins, David Mottram, Eliane Alexandre, Lysiane Richert, Helene Aerts, Richard J. Weaver, Robert P. Jones, Esther Johann, Philip G. Hewitt ...Show all 15 authors... , Magnus Ingelman-Sundberg, Christopher E.P. Goldring, Neil R. Kitteringham, Brian Kevin Park; Show fewer authors
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Toxicol. Sci. 147:412-424(2015)

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Joanna Janiszewska, Marcin Szaumkessel, Magdalena Kostrzewska-Poczekaj, Kinga Bednarek, Julia Paczkowska, Joanna Jackowska, Reidar Grenman, Krzysztof Szyfter, Malgorzata Wierzbicka, Maciej Giefing, Malgorzata Jarmuz-Szymczak;
Global miRNA expression profiling identifies miR-1290 as novel potential oncomiR in laryngeal carcinoma.
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Yu Wu, Xing-Chao Geng, Ju-Feng Wang, Yu-Fa Miao, Yan-Li Lu, Bo Li;
The HepaRG cell line, a superior in vitro model to L-02, HepG2 and hiHeps cell lines for assessing drug-induced liver injury.
Cell Biol. Toxicol. 32:37-59(2016)

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Rho-kinase/myosin light chain kinase pathway plays a key role in the impairment of bile canaliculi dynamics induced by cholestatic drugs.
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Vincent A. van der Mark, Dirk Rudi de Waart, Valery Shevchenko, Ronald P.J. Oude Elferink, Robert A.F.M. Chamuleau, Ruurdtje Hoekstra;
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Drug Metab. Dispos. 45:56-67(2017)

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Yi Ni, Stephan Urban;
Hepatitis B virus infection of HepaRG cells, HepaRG-hNTCP cells, and primary human hepatocytes.
Methods Mol. Biol. 1540:15-25(2017)

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A cell-based assay using HepaRG cells for predicting drug-induced phospholipidosis.
J. Toxicol. Sci. 42:641-650(2017)

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Georg Tascher, Audrey Burban, Sandrine Camus, Marine I. Plumel, Stephanie Chanon, Remy Le Guevel, Valery Shevchenko, Alain Van Dorsselaer, Etienne Lefai, Christiane Guguen-Guillouzo, Fabrice Bertile;
In-depth proteome analysis highlights HepaRG cells as a versatile cell system surrogate for primary human hepatocytes.
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Differential effects on human cytochromes P450 by CRISPR/Cas9-induced genetic knockout of cytochrome P450 reductase and cytochrome b5 in HepaRG cells.
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