Cellosaurus HepaRG CYP3A4G/7R clone 3 (CVCL_JJ68)
| Cell line name | HepaRG CYP3A4G/7R clone 3 |
|---|---|
| Synonyms | HepaRG C3; C3 |
| Accession | CVCL_JJ68 |
| Resource Identification Initiative | To cite this cell line use: HepaRG CYP3A4G/7R clone 3 (RRID:CVCL_JJ68) |
| Comments | Characteristics: Transfected with a dual reporter that express RFP under the transcriptional regulation of CYP3A7 in the hepatoblast-like cell state and EGFP under the transcriptional regulation of CYP3A4. Genetic integration: Method=Transfection/transduction; Gene=FPbase; EGE3L; DsRed (Note=drFP583, red fluorescent protein from Discosoma sp.). Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Derived from site: In situ; Liver; UBERON=UBERON_0002107. |
| Disease | Hepatitis C infection (NCIt: C3098) Hepatocellular carcinoma (NCIt: C3099) Hepatocellular carcinoma (ORDO: Orphanet_88673) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_9720 (HepaRG) |
| Sex of cell | Female |
| Age at sampling | Age unspecified |
| Category | Cancer cell line |
| Publications | PubMed=25101946; DOI=10.1371/journal.pone.0104123; PMCID=PMC4125183 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q54882835 |
| Entry history | |
| Entry creation | 22-Aug-2017 |
| Last entry update | 14-Aug-2025 |
| Version number | 11 |