ID   HepaRG CYP3A4G/7R clone 3
AC   CVCL_JJ68
SY   HepaRG C3; C3
DR   Wikidata; Q54882835
RX   PubMed=25101946;
CC   Characteristics: Transfected with a dual reporter that express RFP under the transcriptional regulation of CYP3A7 in the hepatoblast-like cell state and EGFP under the transcriptional regulation of CYP3A4.
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; EGE3L; DsRed (Note=drFP583, red fluorescent protein from Discosoma sp.).
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
DI   NCIt; C3098; Hepatitis C infection
DI   NCIt; C3099; Hepatocellular carcinoma
DI   ORDO; Orphanet_88673; Hepatocellular carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_9720 ! HepaRG
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 22-08-17; Last updated: 10-04-25; Version: 10
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RX   PubMed=25101946; DOI=10.1371/journal.pone.0104123; PMCID=PMC4125183;
RA   Tsuji S., Kawamura F., Kubiura M., Hayashi A., Ohbayashi T.,
RA   Kazuki Y., Chesne C., Oshimura M., Tada M.;
RT   "Dual-color fluorescence imaging to monitor CYP3A4 and CYP3A7
RT   expression in human hepatic carcinoma HepG2 and HepaRG cells.";
RL   PLoS ONE 9:e104123.1-e104123.14(2014).
//