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Cellosaurus PC-3M (CVCL_9555)

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Cell line name PC-3M
Synonyms PC3-M; PC-3/M; PC3M; Pc3M
Accession CVCL_9555
Resource Identification Initiative To cite this cell line use: PC-3M (RRID:CVCL_9555)
Comments Population: Caucasian.
Characteristics: Established from a xenografted tumor of nude mice injected with the parent cell line (PubMed=447482).
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Children:
CVCL_5J43 (hVEGF-luc/PC3M)CVCL_6E87 (PC-3/MA2)CVCL_G257 (PC-3M-1E8)
CVCL_G256 (PC-3M-2B4)CVCL_L155 (PC-3M-LN1)CVCL_D577 (PC-3M-luc-C6)
CVCL_5J25 (PC-3M-luc2)CVCL_L158 (PC-3M-Pro1)CVCL_5J10 (PC-3M-Red-FLuc)
CVCL_4885 (PC3-MM2)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): KCLB=80020

Markers:
AmelogeninX
CSF1PO11
D3S135816
D5S81813
D7S8208,11
D13S31711
FGA24
TH016,7
TPOX8,9
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=447482
M. Edward Kaighn, K. Shankar Narayan, Yasushi Ohnuki, John F. Lechner, Lawrence W. Jones;
Establishment and characterization of a human prostatic carcinoma cell line (PC-3).
Invest. Urol. 17:16-23(1979)

PubMed=7471073
Yasushi Ohnuki, Maureen M. Marnell, Merrill S. Babcock, John F. Lechner, M. Edward Kaighn;
Chromosomal analysis of human prostatic adenocarcinoma cell lines.
Cancer Res. 40:524-534(1980)

PubMed=7017212; DOI=10.1093/jnci/66.6.1003
Marilyn S. Pollack, Socorro D. Heagney, Philip O. Livingston, Jorgen Fogh;
HLA-A, B, C and DR alloantigen expression on forty-six cultured human tumor cell lines.
J. Natl. Cancer Inst. 66:1003-1012(1981)

PubMed=3335022
Michael Curtis Alley, Dominic A. Scudiero, Anne Monks, Miriam L. Hursey, Maciej J. Czerwinski, Donald L. Fine, Betty Jane Abbott, Joseph G. Mayo, Robert H. Shoemaker, Michael R. Boyd;
Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay.
Cancer Res. 48:589-601(1988)

Cross-references
Cell line collections (Providers) CLS; 305061
KCLB; 80020
KYinno; KC-3937
NCI-DTP; PC-3/M
Cell line databases/resources cancercelllines; CVCL_9555
TOKU-E; 3851
Anatomy/cell type resources BTO; BTO_0005220
Chemistry resources ChEMBL-Cells; CHEMBL4295486
ChEMBL-Targets; CHEMBL4296484
PubChem_Cell_line; CVCL_9555
Encyclopedic resources Wikidata; Q54938435
Experimental variables resources EFO; EFO_0022442
Gene expression databases GEO; GSM1178559
GEO; GSM1178560
GEO; GSM1178561
Polymorphism and mutation databases Cosmic; 1945877
Entry history
Entry creation06-Jun-2012
Last entry update14-Aug-2025
Version number30