Cellosaurus cell line PC-3/MA2 (CVCL

Cellosaurus PC-3/MA2 (CVCL_6E87)

Cross-references
Cell line name	PC-3/MA2
Synonyms	PC-3 MA2; PC3-MA2; PC3mA2; PC3MA2
Accession	CVCL_6E87
Resource Identification Initiative	To cite this cell line use: PC-3/MA2 (RRID:CVCL_6E87)
Comments	Population: Caucasian. Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease	Prostate carcinoma (NCIt: C4863)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_9555 (PC-3M)
Sex of cell	Male
Age at sampling	62Y
Category	Cancer cell line
Publications	PubMed=447482 M. Edward Kaighn, K. Shankar Narayan, Yasushi Ohnuki, John F. Lechner, Lawrence W. Jones; Establishment and characterization of a human prostatic carcinoma cell line (PC-3). Invest. Urol. 17:16-23(1979) PubMed=7459854 David Kirk, Marika F. Szalay, M. Edward Kaighn; Modulation of growth of a human prostatic cancer cell line (PC-3) in agar culture by normal human lung fibroblasts. Cancer Res. 41:1100-1103(1981) PubMed=8612713; DOI=10.1006/excr.1996.0146 Elizabeth S. Woo, Yukihiro Kondo, Simon C. Watkins, Dale G. Hoyt, John Stephen Lazo; Nucleophilic distribution of metallothionein in human tumor cells. Exp. Cell Res. 224:365-371(1996) PubMed=10754530; DOI=10.1002/(SICI)1097-0045(20000501)43:2<144::AID-PROS9>3.0.CO;2-H Yasutomo Suzuki, Yukihiro Kondo, Seiichiro Himeno, Kaoru Nemoto, Masao Akimoto, Nobumasa Imura; Role of antioxidant systems in human androgen-independent prostate cancer cells. Prostate 43:144-149(2000)
Cell line databases/resources	cancercelllines; CVCL_6E87
Encyclopedic resources	Wikidata; Q54938451
Entry history
Entry creation	23-Feb-2016
Last entry update	10-Apr-2025
Version number	13