ID   PC-3M
AC   CVCL_9555
SY   PC3-M; PC-3/M; PC3M; Pc3M
DR   BTO; BTO_0005220
DR   EFO; EFO_0022442
DR   cancercelllines; CVCL_9555
DR   ChEMBL-Cells; CHEMBL4295486
DR   ChEMBL-Targets; CHEMBL4296484
DR   CLS; 305061
DR   Cosmic; 1945877
DR   GEO; GSM1178559
DR   GEO; GSM1178560
DR   GEO; GSM1178561
DR   KCLB; 80020
DR   KYinno; KC-3937
DR   NCI-DTP; PC-3/M
DR   PubChem_Cell_line; CVCL_9555
DR   TOKU-E; 3851
DR   Wikidata; Q54938435
RX   PubMed=447482;
RX   PubMed=3335022;
RX   PubMed=7017212;
RX   PubMed=7471073;
CC   Population: Caucasian.
CC   Characteristics: Established from a xenografted tumor of nude mice injected with the parent cell line (PubMed=447482).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
ST   Source(s): KCLB=80020
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 11
ST   D3S1358: 16
ST   D5S818: 13
ST   D7S820: 8,11
ST   FGA: 24
ST   TH01: 6,7
ST   TPOX: 8,9
ST   vWA: 17
DI   NCIt; C4863; Prostate carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0035 ! PC-3
SX   Male
AG   62Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 14-08-25; Version: 30
CH   CVCL_5J43 ! hVEGF-luc/PC3M
CH   CVCL_6E87 ! PC-3/MA2
CH   CVCL_G257 ! PC-3M-1E8
CH   CVCL_G256 ! PC-3M-2B4
CH   CVCL_L155 ! PC-3M-LN1
CH   CVCL_D577 ! PC-3M-luc-C6
CH   CVCL_5J25 ! PC-3M-luc2
CH   CVCL_L158 ! PC-3M-Pro1
CH   CVCL_5J10 ! PC-3M-Red-FLuc
CH   CVCL_4885 ! PC3-MM2
//
RX   PubMed=3335022;
RA   Alley, Michael C.
RA   Scudiero, Dominic A.
RA   Monks, Anne
RA   Hursey, Miriam L.
RA   Czerwinski, Maciej J.
RA   Fine, Donald L.
RA   Abbott, Betty Jane
RA   Mayo, Joseph G.
RA   Shoemaker, Robert H.
RA   Boyd, Michael R.
RT   "Feasibility of drug screening with panels of human tumor cell lines
RT   using a microculture tetrazolium assay.";
RL   Cancer Res. 48:589-601(1988).
//
RX   PubMed=7471073;
RA   Ohnuki, Yasushi
RA   Marnell, Maureen M.
RA   Babcock, Merrill S.
RA   Lechner, John F.
RA   Kaighn, M. Edward
RT   "Chromosomal analysis of human prostatic adenocarcinoma cell lines.";
RL   Cancer Res. 40:524-534(1980).
//
RX   PubMed=447482;
RA   Kaighn, M. Edward
RA   Narayan, K. Shankar
RA   Ohnuki, Yasushi
RA   Lechner, John F.
RA   Jones, Lawrence W.
RT   "Establishment and characterization of a human prostatic carcinoma
RT   cell line (PC-3).";
RL   Invest. Urol. 17:16-23(1979).
//
RX   PubMed=7017212; DOI=10.1093/jnci/66.6.1003;
RA   Pollack, Marilyn S.
RA   Heagney, Socorro D.
RA   Livingston, Philip O.
RA   Fogh, Jorgen
RT   "HLA-A, B, C and DR alloantigen expression on forty-six cultured human
RT   tumor cell lines.";
RL   J. Natl. Cancer Inst. 66:1003-1012(1981).
//