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Cellosaurus PC-3M-luc-C6 (CVCL_D577)

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Cell line name PC-3M-luc-C6
Accession CVCL_D577
Resource Identification Initiative To cite this cell line use: PC-3M-luc-C6 (RRID:CVCL_D577)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Discontinued: Revvity/PerkinElmer; 119270; true.
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9555 (PC-3M)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Publications

PubMed=14713107; DOI=10.1023/B:CLIN.0000006815.49932.98
Darlene E. Jenkins, Yoko A. Oei, Yvette S. Hornig, Shang-Fan Yu, Joan M. Dusich, Tony Purchio, Pamela R. Contag;
Bioluminescent imaging (BLI) to improve and refine traditional murine models of tumor growth and metastasis.
Clin. Exp. Metastasis 20:733-744(2003)

PubMed=14713108; DOI=10.1023/B:CLIN.0000006817.25962.87
Darlene E. Jenkins, Shang-Fan Yu, Yvette S. Hornig, Tony Purchio, Pamela R. Contag;
In vivo monitoring of tumor relapse and metastasis using bioluminescent PC-3M-luc-C6 cells in murine models of human prostate cancer.
Clin. Exp. Metastasis 20:745-756(2003)

Cross-references
Cell line collections (Providers) Revvity/PerkinElmer; 119270
Cell line databases/resources cancercelllines; CVCL_D577
Encyclopedic resources Wikidata; Q54938443
Entry history
Entry creation22-Oct-2012
Last entry update27-Nov-2025
Version number21