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Cellosaurus CT26 (CVCL_7254)

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Cell line name CT26
Synonyms CT-26; CT 26; Colon Tumor 26
Accession CVCL_7254
Resource Identification Initiative To cite this cell line use: CT26 (RRID:CVCL_7254)
Comments Transformant: ChEBI; CHEBI_82373; N-nitroso-N-methylurethane (NNMU).
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Gene deletion; MGI; MGI:104738; Cdkn2a; Zygosity=Homozygous (from child cell line CT26.WT).
  • Mutation; MGI; MGI:96680; Kras; Simple; p.Gly12Asp (c.35G>A); Zygosity=Homozygous (from child cell line CT26.WT).
Disease Mouse colon adenocarcinoma (NCIt: C120044)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Children:
CVCL_E8GY (CT26-hCD39-LZ)CVCL_E8GZ (CT26-hEpCam-LZ)CVCL_B7NN (CT26-PD-L1 KO)
CVCL_7256 (CT26.WT)CVCL_C9FK (CT26/Cas9-hyg)CVCL_F1NN (HyCyte CT26 KO-mAtm)
CVCL_E1JP (HyCyte CT26 KO-mCd274)CVCL_F4G9 (HyCyte CT26 KO-mChst7)CVCL_F4JC (HyCyte CT26 KO-mF3)
CVCL_F4HR (HyCyte CT26 KO-mFgl2)CVCL_F1NP (HyCyte CT26 KO-mParp1)CVCL_F1NQ (HyCyte CT26 KO-mPrkdc)
CVCL_F4JM (HyCyte CT26 KO-mRnf138)CVCL_D6B1 (HyCyte CT26 KO-mSenp1)CVCL_E1JQ (HyCyte CT26 KO-mTmem176b)
CVCL_F4KR (HyCyte CT26 mKRAS_p.G12C_c.556G＞T cell line)CVCL_F4KX (HyCyte CT26 mKRAS_p.G12C_c.564G＞T cell line)CVCL_F4S2 (HyCyte CT26 stable cell line for mIgfbp2 overexpression)
CVCL_E3H3 (HyCyte CT26-Luc)CVCL_YJ79 (LINTERNA CT-26)
Sex of cell Female
Category Cancer cell line
Web pages Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/c/cell-lines-detail-441.html
Provider; Altogen; Xenograft model; https://altogenlabs.com/xenograft-models/colon-cancer-xenograft/ct26-xenograft-model/
Publications

PubMed=6992981
Michael G. Brattain, Janna Diane Strobel-Stevens, W. David Fine, Maryla Webb, Awni M. Sarrif;
Establishment of mouse colonic carcinoma cell lines with different metastatic properties.
Cancer Res. 40:2142-2146(1980)

Cross-references
Cell line collections (Providers) ABM; T8267
CLS; 305229
KCB; KCB 2012007YJ
KCLB; 80009
NCBI_Iran; C532
Cell line databases/resources Lonza; 1686
TOKU-E; 4093
Anatomy/cell type resources BTO; BTO_0003630
CRISP screens repositories BioGRID_ORCS_Cell_line; 1261
Chemistry resources ChEMBL-Cells; CHEMBL3308079
ChEMBL-Targets; CHEMBL613866
PubChem_Cell_line; CVCL_7254
Encyclopedic resources Wikidata; Q54814707
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number26