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Cellosaurus CT26.WT (CVCL_7256)

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Cell line name CT26.WT
Synonyms CT-26 WT; CT26.wt; CT26WT
Accession CVCL_7256
Resource Identification Initiative To cite this cell line use: CT26.WT (RRID:CVCL_7256)
Comments Transformant: ChEBI; CHEBI_82373; N-nitroso-N-methylurethane (NNMU).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Omics: Variations; Array-based CGH.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Gene deletion; MGI; MGI:104738; Cdkn2a; Zygosity=Homozygous (PubMed=24621249).
  • Mutation; MGI; MGI:96680; Kras; Simple; p.Gly12Asp (c.35G>A); Zygosity=Homozygous (PubMed=24621249).
Disease Mouse colon adenocarcinoma (NCIt: C120044)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_7254 (CT26)
Children:
CVCL_9V16 (CT26-DsRed)CVCL_7255 (CT26.CL25)CVCL_UE29 (CT26.WT human B7H4)
CVCL_XZ50 (CT26.WT human CLDN18.2)CVCL_QZ99 (CT26.WT-eGFP-Puro)CVCL_RA00 (CT26.WT-Fluc-Neo)
CVCL_RA01 (CT26.WT-Fluc-Neo/eGFP-Puro)CVCL_RA02 (CT26.WT-Fluc-Neo/iRFP-Puro)CVCL_RA03 (CT26.WT-iRFP-Neo)
CVCL_RA04 (CT26.WT-iRFP-Neo/mNIS-Puro)CVCL_C8XR (CT26.WT-Luc)CVCL_RA05 (CT26.WT-mNIS (monoclonal))
CVCL_RA06 (CT26.WT-mNIS-Neo/eGFP-Puro)CVCL_RA07 (CT26.WT-mNIS-Neo/Fluc-Puro)CVCL_RA08 (CT26.WT-mNIS-Puro)
CVCL_E6T1 (Genomeditech CT26 H_CLDN18(isoform 2)-eGFP)CVCL_E6T2 (Genomeditech CT26 H_GPA33)CVCL_0A66 (LM17)
CVCL_D8FR (Ubigene CT26.WT Ddr1 KO)CVCL_D8FS (Ubigene CT26.WT Ecm1 KO)CVCL_D8FT (Ubigene CT26.WT Il1r1 KO)
CVCL_D8FU (Ubigene CT26.WT Lrpprc KO)CVCL_D8FV (Ubigene CT26.WT Stat3 KO)CVCL_D8FW (Ubigene CT26.WT Tead1 KO)
CVCL_D8FX (Ubigene CT26.WT Tead4 KO)CVCL_D8FY (Ubigene CT26.WT Tnfrsf1b KO)CVCL_D8FZ (Ubigene CT26.WT Zc3h3 KO)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): PubMed=31220119; Ubigene=YC-B003

Markers:
Mouse STR 1-114,15
Mouse STR 1-217,18
Mouse STR 2-116,17
Mouse STR 3-214
Mouse STR 4-221.3
Mouse STR 5-514
Mouse STR 6-418,20
Mouse STR 6-712
Mouse STR 7-125.2
Mouse STR 8-113
Mouse STR 11-217
Mouse STR 12-116,17
Mouse STR 13-116.2,17.2,18.2
Mouse STR 15-321.3,22.3
Mouse STR 17-215,16,17
Mouse STR 18-319,20
Mouse STR 19-213
Mouse STR X-125,26

Run an STR similarity search on this cell line
Publications

PubMed=7722321; DOI=10.4049/jimmunol.154.9.4685; PMCID=PMC1976248
Michael Wang, Vincenzo Bronte, Pauline W. Chen, Linda Gritz, Dennis Panicali, Steven A. Rosenberg, Nicholas P. Restifo;
Active immunotherapy of cancer with a nonreplicating recombinant fowlpox virus encoding a model tumor-associated antigen.
J. Immunol. 154:4685-4692(1995)

PubMed=11089883; DOI=10.1023/A:1006730320248
Akashi Ikubo, Yasuaki Aoki, Eishi Nagai, Tsuneo Suzuki;
Highly metastatic variant of a mouse colon carcinoma cell line, LM17 and its response to GM-CSF gene therapy.
Clin. Exp. Metastasis 17:849-855(1999)

PubMed=24621249; DOI=10.1186/1471-2164-15-190; PMCID=PMC4007559
John C. Castle, Martin Loewer, Sebastian Boegel, Jos de Graaf, Christian Bender, Arbel D. Tadmor, Valesca Boisguerin, Thomas Bukur, Patrick Sorn, Claudia Paret, Mustafa Diken ...Show all 14 authors... , Sebastian Kreiter, Ozlem Tureci, Ugur Sahin; Show fewer authors
Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma.
BMC Genomics 15:190.1-190.12(2014)

PubMed=25277546; DOI=10.1186/1471-2164-15-847; PMCID=PMC4198738
John Paul Didion, Ryan John Buus, Zohreh Naghashfar, David W. Threadgill, Herbert Carpenter Morse 3rd, Fernando Pardo-Manuel de Villena;
SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy.
BMC Genomics 15:847.1-847.11(2014)

DOI=10.21926/obm.genet.1803037
Hans Rhode, Thomas Liehr, Nadezda Kosyakova, Martina Rincic, Shaymaa S. Hussein Azawi;
Molecular cytogenetic characterization of two murine colorectal cancer cell lines.
OBM Genetics 2:1803037.1-1803037.24(2018)

PubMed=31220119; DOI=10.1371/journal.pone.0218412; PMCID=PMC6586308
Jamie L. Almeida, Aleksandra Dakic, Karin Kindig, Maikan Kone, Deborah Lee Dormady Letham, Scott Langdon, Ruth Peat, Jayamalini Holding-Pillai, Erin M. Hall, Mark Ladd, Megan D. Shaffer ...Show all 23 authors... , Heath Berg, Jin-Liang Li, Georges Wigger, Steve Lund, Carolyn R. Steffen, Barbara B. Fransway, Bob Geraghty, Manuela Natoli, Beth A. Bauer, Susanne M. Gollin, Dale W. Lewis, Yvonne A. Reid; Show fewer authors
Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.
PLoS ONE 14:e0218412.1-e0218412.24(2019)

Cross-references
Cell line collections (Providers) ATCC; CRL-2638
BCRC; 60447
BCRJ; 0402
CLS; 305178
KCB; KCB 201207YJ
Ubigene; YC-B003
Cell line databases/resources CLO; CLO_0002631
CCRID; 1101MOU-PUMC000275
CCRID; 3101MOUTCM37
Anatomy/cell type resources BTO; BTO_0006018
Biological sample resources BioSample; SAMN11397649
Chemistry resources ChEMBL-Cells; CHEMBL4513106
ChEMBL-Targets; CHEMBL4513123
PubChem_Cell_line; CVCL_7256
Encyclopedic resources Wikidata; Q54814710
Entry history
Entry creation04-Apr-2012
Last entry update27-Nov-2025
Version number19