Cellosaurus cell line CT26-PD-L1 KO (CVCL

Cellosaurus CT26-PD-L1 KO (CVCL_B7NN)

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Cell line name

CT26-PD-L1 KO

Synonyms

CT26-Pd-l1 Knockout; genO-CT26-Pd-l1KO

Accession

CVCL_B7NN

Resource Identification Initiative

To cite this cell line use: CT26-PD-L1 KO (RRID:CVCL_B7NN)

Comments

Knockout cell: Method=CRISPR/Cas9; MGI; MGI:1926446; Cd274.
Transformant: ChEBI; CHEBI_82373; N-nitroso-N-methylurethane (NNMU).
Derived from site: In situ; Colon; UBERON=UBERON_0001155.

Sequence variations

Gene deletion; MGI; MGI:104738; Cdkn2a; Zygosity=Homozygous (from parent cell line).
Mutation; MGI; MGI:96680; Kras; Simple; p.Gly12Asp (c.35G>A); Zygosity=Homozygous (from parent cell line).

Disease

Mouse colon adenocarcinoma (NCIt: C120044)

Species of origin

Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.

Hierarchy

Parent: CVCL_7254 (CT26)
Children:

CVCL_B7NP (CT26-hPD-L1)

Sex of cell

Female