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Cellosaurus CT26-hCD39-LZ (CVCL_E8GY)

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Cell line name CT26-hCD39-LZ
Synonyms genO-CT26-hCD39-LZ
Accession CVCL_E8GY
Resource Identification Initiative To cite this cell line use: CT26-hCD39-LZ (RRID:CVCL_E8GY)
Comments Characteristics: Using CRISPR/Cas9 a construct containing a dual fusion reporter luciferase-ZsGreen (LZ) was introduced in one allele of the Rosa2 safe harbor locus (genOway).
Genetic integration: Method=CRISPR/Cas9; Gene=FPbase; W8LAG; ZsGreen (Note=FP506, green fluorescent protein derived from Zoanthus sp).
Genetic integration: Method=CRISPR/Cas9; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Genetic integration: Method=Transfection; Gene=MGI; MGI:102805; Entpd1 (Note=With a fully humanized extracellular domain).
Transformant: ChEBI; CHEBI_82373; N-nitroso-N-methylurethane (NNMU).
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Gene deletion; MGI; MGI:104738; Cdkn2a; Zygosity=Homozygous (from parent cell line).
  • Mutation; MGI; MGI:96680; Kras; Simple; p.Gly12Asp (c.35G>A); Zygosity=Homozygous (from parent cell line).
Disease Mouse colon adenocarcinoma (NCIt: C120044)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_7254 (CT26)
Sex of cell Female
Category Cancer cell line
Web pages Provider; genOway; -; https://www.genoway.com/product/catalog/ct26-hcd39-lz
Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1