Cellosaurus HMCB (CVCL_3317)
Cell line name | HMCB | ||||||||||||||||||
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Synonyms | Human Melanoma Cell Bowes; Bowes melanoma cells; BOWES | ||||||||||||||||||
Accession | CVCL_3317 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: HMCB (RRID:CVCL_3317) | ||||||||||||||||||
Comments | Group: Patented cell line. Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-9607. Population: Caucasian. Omics: Deep exome analysis. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Omics: Transcriptome analysis by RNAseq. Anecdotal: The Bowes cell line is famous for its use in the identification and purification of tissue-type plasminogen activator, tPA. Caution: The exact relationship between HMCB (Cellosaurus=CVCL_3317) and RPMI-7262/7272/7932/7962/7972 is not clear: all are derived from patient 'Bowes' melanoma. | ||||||||||||||||||
Sequence variations |
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HLA typing | Source: PubMed=26589293
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Genome ancestry | Source: PubMed=30894373
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Disease | Melanoma (NCIt: C3224) | ||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||
Hierarchy | Children:
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Originate from same individual | CVCL_T313 ! RPMI-7262 CVCL_T314 ! RPMI-7272 CVCL_T315 ! RPMI-7551 CVCL_T316 ! RPMI-7781 CVCL_T317 ! RPMI-7801 CVCL_T318 ! RPMI-7922 CVCL_2713 ! RPMI-7932 CVCL_T319 ! RPMI-7962 CVCL_T320 ! RPMI-7972 CVCL_T321 ! RPMI-8002 CVCL_T322 ! RPMI-8072 | ||||||||||||||||||
Sex of cell | Female | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): ATCC Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Web pages | https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/b/cell-lines-detail-379.html https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/h/cell-lines-detail-109.html | ||||||||||||||||||
Publications | PubMed=1970678; DOI=10.1007/BF02890069 Patent=US5010002 PubMed=12068308; DOI=10.1038/nature00766 PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458 PubMed=22460905; DOI=10.1038/nature11003 PubMed=26589293; DOI=10.1186/s13073-015-0240-5 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=31068700; DOI=10.1038/s41586-019-1186-3 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections (Providers) | ATCC; CRL-9607
NCBI_Iran; C524 | ||||||||||||||||||
Cell line databases/resources | CLO; CLO_0003785
cancercelllines; CVCL_3317 Cell_Model_Passport; SIDM00914 DepMap; ACH-000931 IGRhCellID; HMCB | ||||||||||||||||||
Anatomy/cell type resources | BTO; BTO:0001998 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN10988240 | ||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308385
ChEMBL-Targets; CHEMBL614824 PharmacoDB; HMCB_553_2019 PubChem_Cell_line; CVCL_3317 | ||||||||||||||||||
Encyclopedic resources | Wikidata; Q54889913 | ||||||||||||||||||
Experimental variables resources | EFO; EFO_0002195 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-38
ArrayExpress; E-MTAB-2770 GEO; GSM827473 GEO; GSM887087 GEO; GSM888157 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 724822
IARC_TP53; 21374 LiGeA; CCLE_295 Progenetix; CVCL_3317 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 05-Oct-2023 | ||||||||||||||||||
Version number | 38 |