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Cellosaurus BOWES CXCR3 clone #3 (CVCL_E7UM)

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Cell line name BOWES CXCR3 clone #3
Accession CVCL_E7UM
Resource Identification Initiative To cite this cell line use: BOWES CXCR3 clone #3 (RRID:CVCL_E7UM)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4540; CXCR3.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Sequence variations
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Trp110Ter (c.330G>A) (p.Gly125Arg, c.373G>A); ClinVar=VCV000376303; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.His193Arg (c.578A>G); ClinVar=VCV000184979; Zygosity=Homozygous (from parent cell line).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3317 (HMCB)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=25798946; DOI=10.1371/journal.pone.0121140; PMCID=PMC4370421
Molly Harris Jenkins, Constance Elizabeth Brinckerhoff, David Warren Mullins;
CXCR3 signaling in BRAFWT melanoma increases IL-8 expression and tumorigenicity.
PLoS ONE 10:e0121140.1-e0121140.17(2015)

Entry history
Entry creation10-Apr-2025
Last entry update14-Aug-2025
Version number2