• Mutation; VGNC; VGNC:42508; KRAS; Simple; p.Glu63Lys (c.187G>A); Zygosity=Heterozygous (PubMed=31175136).
  

PubMed=19147538; DOI=10.1158/1541-7786.MCR-08-0347; PMCID=PMC2653090
Jin Zhang, Xiang-Ling Chen, Michael S. Kent, Carlos O. Rodriguez, Xin-Bin Chen;
Establishment of a dog model for the p53 family pathway and identification of a novel isoform of p21 cyclin-dependent kinase inhibitor.
Mol. Cancer Res. 7:67-78(2009)

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Marie E. Legare, Jamie Bush, Amanda K. Ashley, Taka Kato, William H. Hanneman;
Cellular and phenotypic characterization of canine osteosarcoma cell lines.
J. Cancer 2:262-270(2011)

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Tracy Stokol, Janelle L. Daddona, Lamya S. Mubayed, Jakob Trimpert, Sungkwon Kang;
Evaluation of tissue factor expression in canine tumor cells.
Am. J. Vet. Res. 72:1097-1106(2011)

PubMed=21908323; DOI=10.1177/1040638711408064
Liza E. O'Donoghue, Jason P. Rivest, Dawn L. Duval;
Polymerase chain reaction-based species verification and microsatellite analysis for canine cell line validation.
J. Vet. Diagn. Invest. 23:780-785(2011)

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Ashlee Sonya Urbasic, Stacy Hynes, Amy Joan Somrak, Stacey Contakos, Masmudur M. Rahman, Jia Liu, Amy L. MacNeill;
Oncolysis of canine tumor cells by myxoma virus lacking the serp2 gene.
Am. J. Vet. Res. 73:1252-1261(2012)

PubMed=22916246; DOI=10.1371/journal.pone.0043355; PMCID=PMC3420908
Junko Maeda, Charles R. Yurkon, Hiroshi Fujisawa, Masami Kaneko, Stefan C. Genet, Erica J. Roybal, Garrett Wayne Rota, Ethan R. Saffer, Barbara J. Rose, William H. Hanneman, Douglas H. Thamm, Takamitsu A. Kato;
Genomic instability and telomere fusion of canine osteosarcoma cells.
PLoS ONE 7:e43355.1-e43355.12(2012)

PubMed=23365669; DOI=10.1371/journal.pone.0054464; PMCID=PMC3554772
James W. Wells, Christopher H. Evans, Milcah C. Scott, Barbara C. Rutgen, Timothy D. O'Brien, Jaime F. Modiano, Goran Cvetkovic, Slobodan Tepic;
Arginase treatment prevents the recovery of canine lymphoma and osteosarcoma cells resistant to the toxic effects of prolonged arginine deprivation.
PLoS ONE 8:e54464.1-e54464.9(2013)

PubMed=25190452; DOI=10.1186/s12917-014-0184-9; PMCID=PMC4172958
Lisa Y. Pang, Sally Anne Argyle, Ayako Kamida, Katherine O'Neill Morrison, David John Argyle;
The long-acting COX-2 inhibitor mavacoxib (Trocoxil TM) has anti-proliferative and pro-apoptotic effects on canine cancer cell lines and cancer stem cells in vitro.
BMC Vet. Res. 10:184.1-184.11(2014)

PubMed=27257868; DOI=10.1371/journal.pone.0156689; PMCID=PMC4892608
Junko Maeda, Coral Eva Froning, Colleen A. Brents, Barbara J. Rose, Douglas H. Thamm, Takamitsu A. Kato;
Intrinsic radiosensitivity and cellular characterization of 27 canine cancer cell lines.
PLoS ONE 11:e0156689.1-e0156689.18(2016)

PubMed=26842912; DOI=10.1111/vco.12197
Genevieve Hartley, Erica Ann Faulhaber, Alison Caldwell, Jonathan Coy, Jade N. Kurihara, Amanda Guth, Daniel P. Regan, Steven W. Dow;
Immune regulation of canine tumour and macrophage PD-L1 expression.
Vet. Comp. Oncol. 15:534-549(2017)

PubMed=27197945; DOI=10.1111/vco.12192; PMCID=PMC5656225
Jared S. Fowles, Deanna D. Dailey, Daniel L. Gustafson, Douglas H. Thamm, Dawn L. Duval;
The Flint Animal Cancer Center (FACC) canine tumour cell line panel: a resource for veterinary drug discovery, comparative oncology and translational medicine.
Vet. Comp. Oncol. 15:481-492(2017)

PubMed=31175136; DOI=10.1158/1535-7163.MCT-18-1346; PMCID=PMC6679748
Sunetra Das, Rupa Idate, Kathryn E. Cronise, Daniel L. Gustafson, Dawn L. Duval;
Identifying candidate druggable targets in canine cancer cell lines using whole-exome sequencing.
Mol. Cancer Ther. 18:1460-1471(2019)

PubMed=33126659; DOI=10.3390/ani10111981; PMCID=PMC7693922
Paola Modesto, Jordi Leonardo Castrillo Fernandez, Isabella Martini, Roberto Zoccola, Maria Concetta Pugliano, Chiara Grazia De Ciucis, Maria Goria, Angelo Ferrari, Elisabetta Razzuoli;
Characterization of D-17 canine osteosarcoma cell line and evaluation of its ability to response to infective stressor used as alternative anticancer therapy.
Animals (Basel) 10:1981.1-1981.16(2020)

PubMed=34079834; DOI=10.3389/fvets.2021.666838; PMCID=PMC8165228
Cecilia Gola, Diana Giannuzzi, Andrea Rinaldi, Selina Iussich, Paola Modesto, Emanuela Morello, Paolo Buracco, Luca Aresu, Raffaella De Maria;
Genomic and transcriptomic characterization of canine osteosarcoma cell lines: a valuable resource in translational medicine.
Front. Vet. Sci. 8:666838.1-666838.11(2021)