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Cellosaurus DSN (CVCL_1919)

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Cell line name DSN
Accession CVCL_1919
Resource Identification Initiative To cite this cell line use: DSN (RRID:CVCL_1919)
Comments Group: Patented cell line.
Group: Retrovirus packaging cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-9939.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P03399; Avian reticuloendotheliosis virus env.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P03360; Avian reticuloendotheliosis virus gag-pol.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; VGNC; VGNC:42508; KRAS; Simple; p.Glu63Lys (c.187G>A); Zygosity=Heterozygous (from parent cell line).
Disease Canine osteosarcoma (NCIt: C120045)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Poodle; VBO=VBO_0201048.
Hierarchy Parent: CVCL_1916 (D-17)
Sex of cell Female
Age at sampling 11Y
Category Cancer cell line
Publications

PubMed=2524600; DOI=10.1128/JVI.63.7.3209-3212.1989; PMCID=PMC250885
Joseph P. Dougherty, Rebecca Wisniewski, Shiao-Lan Yang, Brett W. Rhode, Howard Martin Temin;
New retrovirus helper cells with almost no nucleotide sequence homology to retrovirus vectors.
J. Virol. 63:3209-3212(1989)

Patent=US5124263
Howard Martin Temin, Joseph P. Dougherty;
Recombination resistant retroviral helper cell and products produced thereby.
Patent number US5124263, 23-Jun-1992

Cross-references
Cell line collections (Providers) ATCC; CRL-9939
Cell line databases/resources CLO; CLO_0002836
Encyclopedic resources Wikidata; Q54831459
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number20