• Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=11787853).
  
• Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Homozygous (PubMed=7961102; PubMed=8026879; PubMed=11115575; PubMed=11169959; PubMed=11787853; PubMed=12068308; PubMed=21607521; Cosmic-CLP=724870; DepMap=ACH-000601).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Homozygous (PubMed=1630814; PubMed=1764370; PubMed=7961102; PubMed=8026879; PubMed=8194712; PubMed=11115575; PubMed=11169959; PubMed=11787853; PubMed=21607521; Cosmic-CLP=724870; DepMap=ACH-000601).
  

PubMed=832918; DOI=10.1002/ijc.2910190118
Adel A. Yunis, Grace K. Arimura, David J. Russin;
Human pancreatic carcinoma (MIA PaCa-2) in continuous culture: sensitivity to asparaginase.
Int. J. Cancer 19:128-135(1977)

PubMed=1764370; DOI=10.1038/bjc.1991.467; PMCID=PMC1977874
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Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer.
Br. J. Cancer 64:1076-1082(1991)

PubMed=1630814
Bruce Anthony Ruggeri, Shi-Yu Zhang, Jorge Caamano, Marion DiRado, Stuart Dale Flynn, Andres J.P. Klein-Szanto;
Human pancreatic carcinomas and cell lines reveal frequent and multiple alterations in the p53 and Rb-1 tumor-suppressor genes.
Oncogene 7:1503-1511(1992)

PubMed=7809022; DOI=10.1097/00006676-199409000-00018
Shoichiro Sumi, R. Daniel Beauchamp, Courtney M. Townsend Jr., Parviz M. Pour, Jin Ishizuka, James C. Thompson;
Lovastatin inhibits pancreatic cancer growth regardless of RAS mutation.
Pancreas 9:657-661(1994)

PubMed=7961102; DOI=10.1111/j.1349-7006.1994.tb02898.x; PMCID=PMC5919355
Hirofumi Suwa, Tsunehiro Yoshimura, Nozomi Yamaguchi, Kazunori Kanehira, Tadao Manabe, Masayuki Imamura, Hiroshi Hiai, Manabu Fukumoto;
K-ras and p53 alterations in genomic DNA and transcripts of human pancreatic adenocarcinoma cell lines.
Jpn. J. Cancer Res. 85:1005-1014(1994)

PubMed=8026879; DOI=10.1002/ijc.2910580207
Georgina Berrozpe, James Schaeffer, Miguel Angel Peinado, Francisco X. Real, Manuel Perucho;
Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer.
Int. J. Cancer 58:185-191(1994)

PubMed=8194712; DOI=10.1016/0016-5085(94)90422-7
Babette Simon, Rolf Weinel, Martin Hohne, Jutta Watz, Jorg Schmidt, Gunther Kortner, Rudolf Arnold;
Frequent alterations of the tumor suppressor genes p53 and DCC in human pancreatic carcinoma.
Gastroenterology 106:1645-1651(1994)

PubMed=21607521; DOI=10.3892/or.1.6.1223
Haruo Iguchi, Ryoji Morita, Daisuke Yasuda, Ryoichi Takayanagi, Yurika Ikeda, Yutaka Takada, Takao Shimazoe, Hajime Nawata, Akira Kono;
Alterations of the p53 tumor-suppressor gene and ki-ras oncogene in human pancreatic cancer-derived cell-lines with different metastatic potential.
Oncol. Rep. 1:1223-1227(1994)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Li-Qun Jia, Motonobu Osada, Chikashi Ishioka, Makio Gamo, Shuntaro Ikawa, Takao Suzuki, Hideki Shimodaira, Tomohito Niitani, Toshio Kudo, Mitoshi Akiyama, Narimiti Kimura, Mitsuyoshi Matsuo, Hiroshi Mizusawa ...Show all 18 authors... , Noriho Tanaka, Hideki Koyama, Masayoshi Namba, Ryunosuke Kanamaru, Toshio Kuroki; Show fewer authors
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=10027410; DOI=10.1016/S0002-9440(10)65298-4; PMCID=PMC1850008
B. Michael Ghadimi, Evelin Schrock, Robert L. Walker, Danny Wangsa, Annukka Jauho, Paul S. Meltzer, Thomas Ried;
Specific chromosomal aberrations and amplification of the AIB1 nuclear receptor coactivator gene in pancreatic carcinomas.
Am. J. Pathol. 154:525-536(1999)

PubMed=11115575; DOI=10.3892/or.8.1.89
Chun-Lan Sun, Takashi Yamato, Toru Furukawa, Yasuyuki Ohnishi, Hiroshi Kijima, Akira Horii;
Characterization of the mutations of the K-ras, p53, p16, and SMAD4 genes in 15 human pancreatic cancer cell lines.
Oncol. Rep. 8:89-92(2001)

PubMed=11169957; DOI=10.1002/1097-0215(200002)9999:9999<::AID-IJC1014>3.0.CO;2-U
Christine Wallrapp, Susanne Hahnel, Wolfgang Boeck, Anja Soder, Antoaneta Mincheva, Peter Lichter, Gerhard Leder, Frank Gansauge, Claudio Sorio, Aldo Scarpa, Thomas M. Gress;
Loss of the Y chromosome is a frequent chromosomal imbalance in pancreatic cancer and allows differentiation to chronic pancreatitis.
Int. J. Cancer 91:340-344(2001)

PubMed=11169959; DOI=10.1002/1097-0215(200002)9999:9999<::AID-IJC1049>3.0.CO;2-C
Vorapan Sirivatanauksorn, Yongyut Sirivatanauksorn, Patricia A. Gorman, Jeffrey M. Davidson, Denise Sheer, Patrick S. Moore, Aldo Scarpa, Paul A.W. Edwards, Nicholas Robert Lemoine;
Non-random chromosomal rearrangements in pancreatic cancer cell lines identified by spectral karyotyping.
Int. J. Cancer 91:350-358(2001)

PubMed=11787853; DOI=10.1007/s004280100474
Patrick S. Moore, Bence Sipos, Simonetta Orlandini, Claudio Sorio, Francisco X. Real, Nicholas Robert Lemoine, Thomas M. Gress, Claudio Bassi, Gunter Kloppel, Holger Kalthoff, Hendrik Ungefroren, Johannes-Matthias Lohr, Aldo Scarpa; Show fewer authors ...Show all 13 authors...
Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4.
Virchows Arch. 439:798-802(2001)

PubMed=12068308; DOI=10.1038/nature00766
Helen R. Davies, Graham Robert Bignell, Charles Cox, Philip J. Stephens, Sarah Edkins, Sheila Clegg, Jon W. Teague, Hayley Woffendin, Mathew J. Garnett, William Bottomley, Neil Davis, Ed Dicks, Rebecca Ewing ...Show all 52 authors... , Yvonne Floyd, Kristian Gray, Sarah Hall, Rachel Hawes, Jaime Hughes, Vivian Kosmidou, Andrew Menzies, Catherine Mould, Adrian Parker, Claire Stevens, Stephen Watt, Steven Hooper, Rebecca Wilson, Hiran Jayatilake, Barry Austin Gusterson, Colin S. Cooper, Janet M. Shipley, Darren Hargrave, Kathy Pritchard-Jones, Norman J. Maitland, Georgia Chenevix-Trench, Gregory J. Riggins, Darell Doty Bigner, Giuseppe Palmieri, Antonio Cossu, Adrienne M. Flanagan, Andrew Nicholson, Judy W.C. Ho, Suet Yi Leung, Siu Tsan Yuen, Barbara L. Weber, Hilliard Foster Seigler, Timothy L. Darrow, Hugh F. Paterson, Richard Marais, Christopher John Marshall, Richard Wooster, Michael Rudolf Stratton, P. Andrew Futreal; Show fewer authors
Mutations of the BRAF gene in human cancer.
Nature 417:949-954(2002)

PubMed=12692724; DOI=10.1007/s00428-003-0784-4
Bence Sipos, Simone Moser, Holger Kalthoff, Virag Torok, Johannes-Matthias Lohr, Gunter Kloppel;
A comprehensive characterization of pancreatic ductal carcinoma cell lines: towards the establishment of an in vitro research platform.
Virchows Arch. 442:444-452(2003)

PubMed=14695172
Christine A. Iacobuzio-Donahue, Raheela Ashfaq, Anirban Maitra, Nazmi Volkan Adsay, Grace L.-C. Shen-Ong, Karin Berg, Michael Anthony Hollingsworth, John Lemuel Cameron, Charles J. Yeo, Scott E. Kern, Michael Gilbert Goggins, Ralph H. Hruban;
Highly expressed genes in pancreatic ductal adenocarcinomas: a comprehensive characterization and comparison of the transcription profiles obtained from three major technologies.
Cancer Res. 63:8614-8622(2003)

PubMed=15770730; DOI=10.3748/wjg.v11.i10.1521; PMCID=PMC4305696
Jian-Hua Ma, Emilia Patrut, Jan Schmidt, Hanns-Peter Knaebel, Markus Wolfgang Buchler, Alexandra Marten;
Synergistic effects of interferon-alpha in combination with chemoradiation on human pancreatic adenocarcinoma.
World J. Gastroenterol. 11:1521-1528(2005)

PubMed=16912165; DOI=10.1158/0008-5472.CAN-06-0721
Eric S. Calhoun, Tomas Hucl, Eike Gallmeier, Kristen M. West, Dan E. Arking, Anirban Maitra, Christine A. Iacobuzio-Donahue, Aravinda Chakravarti, Ralph H. Hruban, Scott E. Kern;
Identifying allelic loss and homozygous deletions in pancreatic cancer without matched normals using high-density single-nucleotide polymorphism arrays.
Cancer Res. 66:7920-7928(2006)

PubMed=17254797; DOI=10.1016/j.biologicals.2006.10.001
Shahram Azari, Nahid Ahmadi, Mahmood Jeddi-Tehrani, Fazel Shokri;
Profiling and authentication of human cell lines using short tandem repeat (STR) loci: report from the National Cell Bank of Iran.
Biologicals 35:195-202(2007)

PubMed=18298655; DOI=10.1111/j.1582-4934.2008.00289.x; PMCID=PMC3828895
Christian Pilarsky, Ole Ammerpohl, Bence Sipos, Edgar Dahl, Arndt Hartmann, Axel Wellmann, Till Braunschweig, Johannes-Matthias Lohr, Ralf Jesenofsky, Helmut Friess, Moritz Nicolas Wente, Glen Kristiansen, Beatrix Jahnke ...Show all 20 authors... , Axel Denz, Felix Ruckert, Hans Konrad Schackert, Gunter Kloppel, Holger Kalthoff, Hans-Detlev Saeger, Robert Grutzmann; Show fewer authors
Activation of Wnt signalling in stroma from pancreatic cancer identified by gene expression profiling.
J. Cell. Mol. Med. 12:2823-2835(2008)

PubMed=18380791; DOI=10.1111/j.1349-7006.2008.00779.x; PMCID=PMC11158928
Ayako Suzuki, Tatsuhiro Shibata, Yutaka Shimada, Yoshinori Murakami, Akira Horii, Keiko Shiratori, Setsuo Hirohashi, Johji Inazawa, Issei Imoto;
Identification of SMURF1 as a possible target for 7q21.3-22.1 amplification detected in a pancreatic cancer cell line by in-house array-based comparative genomic hybridization.
Cancer Sci. 99:986-994(2008)

PubMed=18575732; DOI=10.3892/or.20.1.155
Toru Kawaoka, Masaaki Oka, Motonari Takashima, Tomio Ueno, Koutaro Yamamoto, Noboru Yahara, Shigefumi Yoshino, Shoichi Hazama;
Adoptive immunotherapy for pancreatic cancer: cytotoxic T lymphocytes stimulated by the MUC1-expressing human pancreatic cancer cell line YPK-1.
Oncol. Rep. 20:155-163(2008)

DOI=10.22029/jlupub-12385
Laura Oberlin;
Treatment of pancreatic carcinoma cell lines in vitro and vivo with a monoclonal antibody against the transferrin receptor.
Thesis VMD (2009); Justus-Liebig-Universitat Giessen; Giessen; Germany

PubMed=19077451; DOI=10.1159/000178871
Tomohiko Harada, Claude Chelala, Tatjana Crnogorac-Jurcevic, Nicholas Robert Lemoine;
Genome-wide analysis of pancreatic cancer using microarray-based techniques.
Pancreatology 9:13-24(2009)

PubMed=19188929; DOI=10.1038/tpj.2008.20
Jun Guo, Mark G. Anderson, Paul Tapang, Joann P. Palma, Luis E. Rodriguez, Amanda L. Niquette, Jun-Ling Li, Jennifer J. Bouska, G. Wang, Dimitri Semizarov, Daniel H. Albert, Cherrie K. Donawho, Keith B. Glaser ...Show all 14 authors... , O. Jameel Shah; Show fewer authors
Identification of genes that confer tumor cell resistance to the aurora B kinase inhibitor, AZD1152.
Pharmacogenomics J. 9:90-102(2009)

PubMed=20037478; DOI=10.4161/cbt.8.21.9685; PMCID=PMC2824894
Oliver A. Kent, Michael E. Mullendore, Eric A. Wentzel, Pedro Lopez-Romero, Aik-Choon Tan, Hector Alvarez, Kristen M. West, Michael F. Ochs, Manuel Hidalgo, Dan E. Arking, Anirban Maitra, Joshua T. Mendell;
A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells.
Cancer Biol. Ther. 8:2013-2024(2009)

PubMed=19904223; DOI=10.1097/MPA.0b013e3181bc44dd; PMCID=PMC2835986
Jing Xiao, Wai-Nang Paul Lee, Ying-Chun Zhao, Rui Cao, Vay Liang-W. Go, Robert R. Recker, Qi Wang, Gary Gui-Shan Xiao;
Profiling pancreatic cancer-secreted proteome using 15N amino acids and serum-free media.
Pancreas 39:e17-e23(2010)

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Graham Robert Bignell, Christopher D. Greenman, Helen R. Davies, Adam P. Butler, Sarah Edkins, Jenny M. Andrews, Gemma Buck, Lina Chen, David Beare, Calli Latimer, Sara Widaa, Jonathan Hinton, Ciara Fahey ...Show all 22 authors... , Bei-Yuan Fu, Sajani Swamy, Gillian L. Dalgliesh, Bin Tean Teh, Panos Deloukas, Feng-Tang Yang, Peter J. Campbell, P. Andrew Futreal, Michael Rudolf Stratton; Show fewer authors
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
S. Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera, Rui Wang, Angela Tam ...Show all 22 authors... , Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=20418756; DOI=10.1097/MPA.0b013e3181c15963; PMCID=PMC2860631
Emily L. Deer, Jessica Gonzalez-Hernandez, Jill D. Coursen, Jill E. Shea, Josephat Gichuhi Ngatia, Courtney Lynne Scaife, Matthew A. Firpo, Sean Jordan Mulvihill;
Phenotype and genotype of pancreatic cancer cell lines.
Pancreas 39:425-435(2010)

PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027
Jordi Ginesta Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A. Margolin, Sungjoon Kim, Christopher J. Wilson, Joseph Lehar, Gregory V. Kryukov, Dmitriy Sonkin, Anupama Reddy, Manway Liu, Lauren Murray ...Show all 61 authors... , Michael F. Berger, John E. Monahan, Paula Morais, Jodi Meltzer, Adam Korejwa, Judit Jane-Valbuena, Felipa A. Mapa, Joseph Thibault, Eva Bric-Furlong, Pichai Raman, Aaron Shipway, Ingo H. Engels, Jill Cheng, Guo-Ying K. Yu, Jian-Jun Yu, Peter Aspesi Jr., Melanie de Silva, Kalpana Jagtap, Michael D. Jones, Li Wang, Charles Hatton, Emanuele Palescandolo, Supriya Gupta, Scott Mahan, Carrie Sougnez, Robert C. Onofrio, Ted Liefeld, Laura E. MacConaill, Wendy Winckler, Michael Reich, Nan-Xin Li, Jill P. Mesirov, Stacey B. Gabriel, Gad Getz, Kristin Ardlie, Vivien Chan, Vic E. Myer, Barbara L. Weber, Jeff Porter, Markus Warmuth, Peter Finan, Jennifer L. Harris, Matthew Langer Meyerson, Todd Robert Golub, Michael P. Morrissey, William Raj Sellers, Robert Schlegel, Levi Alexander Garraway; Show fewer authors
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=22585861; DOI=10.1158/2159-8290.CD-11-0224; PMCID=PMC5057396
Richard Marcotte, Kevin R. Brown, Fernando Jose Suarez Saiz, Azin Sayad, Konstantina Karamboulas, Paul M. Krzyzanowski, Fabrice Sircoulomb, Mauricio Medrano, Yaroslav Fedyshyn, Judice Lie-Yong Koh, Dewald van Dyk, Bohdana Fedyshyn, Marianna Luhova ...Show all 28 authors... , Glauber C. Brito, Franco J. Vizeacoumar, Frederick S. Vizeacoumar, Alessandro Datti, Dahlia Kasimer, Alla Buzina, Patricia Mero, Christine Misquitta, Josee Normand, Maliha Haider, Troy Ketela, Jeffrey L. Wrana, Robert Rottapel, Benjamin G. Neel, Jason Moffat; Show fewer authors
Essential gene profiles in breast, pancreatic, and ovarian cancer cells.
Cancer Discov. 2:172-189(2012)

DOI=10.4172/2324-9293.1000104
Markus Udo Wagenhauser, Felix Ruckert, Marco Niedergethmann, Robert Grutzmann, Hans-Detlev Saeger;
Distribution of characteristic mutations in native ductal adenocarcinoma of the pancreas and pancreatic cancer cell lines.
Cell Biol. Res. Ther. 2:1000104.1-1000104.5(2013)

PubMed=23386380; DOI=10.1002/jcb.24506
Bipasha Bose, P. Sudheer Shenoy;
Non insulin producing cell line, MIA PaCa-2 is rendered insulin producing in vitro via mesenchymal epithelial transition.
J. Cell. Biochem. 114:1642-1652(2013)

PubMed=25167228; DOI=10.1038/bjc.2014.475; PMCID=PMC4453732
Habib Hamidi, Ming Lu, Kevin Chau, Lee Anderson, Marlena Schoenberg Fejzo, Charles Ginther, Ronald Linnartz, Angela Zubel, Dennis Joseph Slamon, Richard Samuel Finn;
KRAS mutational subtype and copy number predict in vitro response of human pancreatic cancer cell lines to MEK inhibition.
Br. J. Cancer 111:1788-1801(2014)

PubMed=25984343; DOI=10.1038/sdata.2014.35; PMCID=PMC4432652
Glenn S. Cowley, Barbara A. Weir, Francisca Vazquez, Pablo Tamayo, Justine A. Scott, Scott Rusin, Alexandra East-Seletsky, Levi D. Ali, William F.J. Gerath, Sarah E. Pantel, Patrick Hall Lizotte, Guo-Zhi Jiang, Jessica Hsiao ...Show all 40 authors... , Aviad Tsherniak, Elizabeth Dwinell, Simon Aoyama, Michael Okamoto, William Harrington, Ellen T. Gelfand, Thomas M. Green, Mark J. Tomko, Shuba Gopal, Terence C. Wong, Hu-Bo Li, Sara Howell, Nicolas Stransky, Ted Liefeld, Dongkeun Jang, Jonathan Bistline, Barbara Hill Meyers, Scott Allen Armstrong, Kenneth Carl Anderson, Kimberly Stegmaier, Michael Reich, David Pellman, Jesse S. Boehm, Jill P. Mesirov, Todd Robert Golub, David E. Root, William Chun Hahn; Show fewer authors
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Sci. Data 1:140035.1-140035.12(2014)

PubMed=25485619; DOI=10.1038/nbt.3080
Christiaan Klijn, Steffen Durinck, Eric W. Stawiski, Peter M. Haverty, Zhao-Shi Jiang, Han-Bin Liu, Jeremiah Degenhardt, Oleg Mayba, Florian Gnad, Jin-Feng Liu, Gregoire Pau, Jens Reeder, Yi Cao ...Show all 30 authors... , Kiran Mukhyala, Suresh K. Selvaraj, Ma-Mie Yu, Gregory J. Zynda, Matthew J. Brauer, Thomas D. Wu, Robert Clifford Gentleman, Gerard Manning, Robert L. Yauch, Richard Bourgon, David Stokoe, Zora Modrusan, Richard M. Neve, Frederic J. de Sauvage, Jeffrey Settleman, Somasekar Seshagiri, Ze-Min Zhang; Show fewer authors
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=25485960; DOI=10.4161/15384047.2014.986967; PMCID=PMC4623403
Betty Kumiko Samulitis, Kelvin W. Pond, Erika Pond, Anne Elizabeth Cress, Hitendra Patel, Lee Wisner, Charmi Patel, Robert T. Dorr, Terry H. Landowski;
Gemcitabine resistant pancreatic cancer cell lines acquire an invasive phenotype with collateral hypersensitivity to histone deacetylase inhibitors.
Cancer Biol. Ther. 16:43-51(2015)

PubMed=25877200; DOI=10.1038/nature14397
Ma-Mie Yu, Suresh K. Selvaraj, May M.Y. Liang-Chu, Sahar Aghajani, Matthew Busse, Jean Yuan, Genee Lee, Franklin V. Peale, Christiaan Klijn, Richard Bourgon, Joshua S. Kaminker, Richard M. Neve;
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

PubMed=26216984; DOI=10.1073/pnas.1501605112; PMCID=PMC4538616
Anneleen Daemen, David Peterson, Nisebita Sahu, Ron McCord, Xiang-Nan Du, Bonnie Liu, Katarzyna Kowanetz, Rebecca Hong, John Moffat, Min Gao, Aaron Boudreau, Rana Mroue, Laura Corson ...Show all 22 authors... , Thomas O'Brien, Jing Qing, Deepak Sampath, Mark Merchant, Robert L. Yauch, Gerard Manning, Jeffrey Settleman, Georgia Hatzivassiliou, Marie Evangelista; Show fewer authors
Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors.
Proc. Natl. Acad. Sci. U.S.A. 112:E4410-E4417(2015)

PubMed=26884312; DOI=10.1038/srep21648; PMCID=PMC4756684
Rui Gradiz, Henriqueta Coimbra Silva, Lina Carvalho, Maria Filomena Botelho, Anabela Mota-Pinto;
MIA PaCa-2 and PANC-1 -- pancreas ductal adenocarcinoma cell lines with neuroendocrine differentiation and somatostatin receptors.
Sci. Rep. 6:21648-21648(2016)

PubMed=27067801; DOI=10.1186/s12885-016-2297-y; PMCID=PMC4828819
Kotaro Miura, Kenjiro Kimura, Ryosuke Amano, Sadaaki Yamazoe, Go Ohira, Akihiro Murata, Kohei Nishio, Tsuyoshi Hasegawa, Masakazu Yashiro, Bunzo Nakata, Masaichi Ohira, Kosei Hirakawa;
Establishment and characterization of new cell lines of anaplastic pancreatic cancer, which is a rare malignancy: OCUP-A1 and OCUP-A2.
BMC Cancer 16:268.1-268.13(2016)

PubMed=27259358; DOI=10.1074/mcp.M116.058313; PMCID=PMC4974343
Emily S. Humphrey, Shih-Ping Su, Adnan M. Nagrial, Falko Hochgrafe, Marina Pajic, Gillian M. Lehrbach, Robert G. Parton, Alpha S. Yap, Lisa G. Horvath, David K. Chang, Andrew Victor Biankin, Jian-Min Wu, Roger J. Daly; Show fewer authors ...Show all 13 authors...
Resolution of novel pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling.
Mol. Cell. Proteomics 15:2671-2685(2016)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469
Francesco Iorio, Theo A. Knijnenburg, Daniel J. Vis, Graham Robert Bignell, Michael Patrick Menden, Michael Schubert, Nanne Aben, Emanuel Goncalves, Syd Barthorpe, Howard Lightfoot, Thomas Cokelaer, Patricia Greninger, Ewald van Dyk ...Show all 39 authors... , Han Chang, Heshani de Silva, Holger Heyn, Xian-Ming Deng, Regina K. Egan, Qing-Song Liu, Tatiana Mironenko, Xeni Mitropoulos, Laura Richardson, Jin-Hua Wang, Ting-Hu Zhang, Sebastian Moran, Sergi Sayols, Maryam Soleimani, David Tamborero, Nuria Lopez-Bigas, Petra Ross-Macdonald, Manel Esteller, Nathanael S. Gray, Daniel Arie Haber, Michael Rudolf Stratton, Cyril Henri Benes, Lodewyk F.A. Wessels, Julio Saez-Rodriguez, Ultan McDermott, Mathew J. Garnett; Show fewer authors
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
Jun Li, Wei Zhao, Rehan Akbani, Wen-Bin Liu, Zhen-Lin Ju, Shi-Yun Ling, Christopher P. Vellano, Paul Roebuck, Qing-Hua Yu, A. Karina Eterovic, Lauren Averett Byers, Michael A. Davies, Wan-Leng Deng ...Show all 25 authors... , Y.N. Vashisht Gopal, Guo Chen, Erika Maria von Euw, Dennis Joseph Slamon, Dylan Conklin, John Victor Heymach, Adi F. Gazdar, John D. Minna, Jeffrey N. Myers, Yi-Ling Lu, Gordon B. Mills, Han Liang; Show fewer authors
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=29444439; DOI=10.1016/j.celrep.2018.01.051; PMCID=PMC6343826
Tina L. Yuan, Arnaud Amzallag, Rachel Bagni, Ming Yi, Shervin Afghani, William Burgan, Nicole Fer, Leslie A. Strathern, Katie Powell, Brian Smith, Andrew Michael Waters, David Alan Drubin, Ty Thomson ...Show all 30 authors... , Rosy Liao, Patricia Greninger, Giovanna T. Stein, Ellen Murchie, Eliane Cortez, Regina K. Egan, Lauren Procter, Matthew Bess, Kwong Tai Cheng, Chih-Shia Lee, Liam Changwoo Lee, Christof Fellmann, Robert Stephens, Ji Luo, Scott William Lowe, Cyril Henri Benes, Frank McCormick; Show fewer authors
Differential effector engagement by oncogenic KRAS.
Cell Rep. 22:1889-1902(2018)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=30971826; DOI=10.1038/s41586-019-1103-9
Fiona M. Behan, Francesco Iorio, Gabriele Picco, Emanuel Goncalves, Charlotte M. Beaver, Giorgia Migliardi, Rita Santos, Yanhua Rao, Francesco Sassi, Marika Pinnelli, Rizwan Ansari, Sarah Harper, David Adam Jackson ...Show all 25 authors... , Rebecca McRae, Rachel Pooley, Piers Wilkinson, Dieudonne J. van der Meer, David Dow, Carolyn A. Buser-Doepner, Andrea Bertotti, Livio Trusolino, Euan Alexander Stronach, Julio Saez-Rodriguez, Kosuke Yusa, Mathew J. Garnett; Show fewer authors
Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.
Nature 568:511-516(2019)

PubMed=31037374; DOI=10.1007/s00216-019-01814-1
Simon Lagies, Manuel Schlimpert, Lukas M. Braun, Michel Kather, Johannes Plagge, Thalia Erbes, Uwe A. Wittel, Bernd Kammerer;
Unraveling altered RNA metabolism in pancreatic cancer cells by liquid-chromatography coupling to ion mobility mass spectrometry.
Anal. Bioanal. Chem. 411:6319-6328(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
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