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Cellosaurus LS180 (CVCL_0397)

[Text version]
Cell line name LS180
Synonyms LS-180; LS 180; Laboratory of Surgery 180
Accession CVCL_0397
Resource Identification Initiative To cite this cell line use: LS180 (RRID:CVCL_0397)
Comments Group: Patented cell line.
Part of: AstraZeneca Colorectal cell line (AZCL) panel.
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Part of: KuDOS 95 cell line panel.
Part of: NCI RAS program mutant KRAS cell line panel.
Part of: RAS genetic alteration cell panel (ATCC TCP-1031).
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CL-187.
Population: Caucasian.
Doubling time: 72 hours (PubMed=7370982).
Microsatellite instability: Instable (MSI-high) (PubMed=24755471; PubMed=25926053; PubMed=31068700; Sanger).
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Glycomics; N-glycan profiling.
Omics: Phenotyping; CRISPR screening.
Omics: Phenotyping; Drug screening.
Omics: Proteomics.
Omics: Proteomics; PTM; Phosphorylation; Quantitative.
Omics: Proteomics; Quantitative.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Cell type: Epithelial cell of colon; CL=CL_0011108.
Sequence variations
HLA typing Source: ATCC=CL-187
Class I
HLA-AA*02
HLA-BB*13,50

Source: PubMed=26589293
Class I
HLA-AA*30:01,30:01
HLA-BB*07:12,15:50
HLA-CC*04:01,06:02
Genome ancestry Source: PubMed=30894373

Origin% genome
African1.1
Native American0
East Asian, North0.33
East Asian, South0.79
South Asian7.05
European, North35.25
European, South55.48
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_KS51 (CellSensor CYP1A1-bla LS-180)CVCL_1384 (LS174T)CVCL_D4V2 (LS180-MFSD3-KO-c4)
CVCL_D4V3 (LS180-MFSD3-KO-c6)CVCL_D4V4 (LS180-NIPAL1-KO-c11)CVCL_D4V5 (LS180-NIPAL1-KO-c3)
CVCL_D4V6 (LS180-SLC10A6-KO-c3)CVCL_D4V7 (LS180-SLC10A6-KO-c8)CVCL_D4V8 (LS180-SLC12A2-KO-c11)
CVCL_D4V9 (LS180-SLC12A2-KO-c9)CVCL_D4VA (LS180-SLC16A14-KO-c1)CVCL_D4VB (LS180-SLC16A14-KO-c8)
CVCL_D4VC (LS180-SLC1A4-KO-c6)CVCL_D4VD (LS180-SLC1A4-KO-c9)CVCL_D4VE (LS180-SLC22A18-KO-c3)
CVCL_D4VF (LS180-SLC22A18-KO-c5)CVCL_D4VG (LS180-SLC25A35-KO-c2)CVCL_D4VH (LS180-SLC25A35-KO-c3)
CVCL_D4VI (LS180-SLC27A3-KO-c1)CVCL_D4VJ (LS180-SLC27A3-KO-c6)CVCL_D4VK (LS180-SLC28A2-KO-c1)
CVCL_D4VL (LS180-SLC28A2-KO-c3)CVCL_D4VM (LS180-SLC28A3-KO-c13)CVCL_D4VN (LS180-SLC28A3-KO-c19)
CVCL_D4VP (LS180-SLC2A12-KO-c3)CVCL_D4VQ (LS180-SLC2A12-KO-c4)CVCL_D4VR (LS180-SLC2A4-KO-c5)
CVCL_D4VS (LS180-SLC2A4-KO-c7)CVCL_D4VT (LS180-SLC2A5-KO-c6)CVCL_D4VU (LS180-SLC2A5-KO-c7)
CVCL_D4VV (LS180-SLC2A9-KO-c2)CVCL_D4VW (LS180-SLC2A9-KO-c3)CVCL_D4VX (LS180-SLC37A1-KO-c2)
CVCL_D4VY (LS180-SLC37A1-KO-c3)CVCL_D4VZ (LS180-SLC46A3-KO-c1)CVCL_D4W0 (LS180-SLC46A3-KO-c5)
CVCL_D4W1 (LS180-SLC52A1-KO-c6)CVCL_D4W2 (LS180-SLC52A1-KO-c8)CVCL_D4W3 (LS180-SLC52A3-KO-c10)
CVCL_D4W4 (LS180-SLC52A3-KO-c13)CVCL_D4W5 (LS180-SLC5A1-KO-c4)CVCL_D4W6 (LS180-SLC5A1-KO-c5)
CVCL_D4W7 (LS180-SLC6A14-KO-c13)CVCL_D4W8 (LS180-SLC6A14-KO-c5)CVCL_D4W9 (LS180-SLC6A20-KO-c2)
CVCL_D4WA (LS180-SLC6A20-KO-c4)CVCL_D4WB (LS180-SLC7A4-KO-c3)CVCL_D4WC (LS180-SLC7A4-KO-c4)
CVCL_D4WD (LS180-SLC9A2-KO-c2)CVCL_D4WE (LS180-SLC9A2-KO-c8)CVCL_D4WF (LS180-SLCO1B3-KO-c10)
CVCL_D4WG (LS180-SLCO1B3-KO-c7)CVCL_D4WH (LS180-SLCO3A1-KO-c7)CVCL_D4WI (LS180-SLCO3A1-KO-c9)
CVCL_D4WJ (LS180-SLCO5A1-KO-c2)CVCL_D4WK (LS180-SLCO5A1-KO-c9)CVCL_D4WL (LS180-SPNS2-KO-c15)
CVCL_D4WM (LS180-SPNS2-KO-c19)CVCL_D4WN (LS180-SPNS3-KO-c3)CVCL_D4WP (LS180-SPNS3-KO-c6)
Sex of cell Female
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): AddexBio=C0009006/56; ATCC=CL-187; CCRID=1101HUM-PUMC000284; Cosmic-CLP=998189; PubMed=25877200; PubMed=25926053

Markers:
AmelogeninX
CSF1PO10,12 (CCRID=1101HUM-PUMC000284)
10,13 (AddexBio=C0009006/56; ATCC=CL-187; Cosmic-CLP=998189; PubMed=25877200; PubMed=25926053)
D2S133818,22
D3S135815,17
D5S81810,15
D7S8209.3,11 (AddexBio=C0009006/56; ATCC=CL-187; Cosmic-CLP=998189; PubMed=25877200)
10,11 (PubMed=25926053)
10.3,11 (CCRID=1101HUM-PUMC000284)
D8S117912,16
D13S31710
D16S53911,12 (CCRID=1101HUM-PUMC000284)
11,13 (AddexBio=C0009006/56; ATCC=CL-187; Cosmic-CLP=998189; PubMed=25877200; PubMed=25926053)
D18S5111,13
D19S43314,15
D21S1129,31
FGA21,22
Penta D10
Penta E15,16
TH016,7
TPOX8,9
vWA15,18

Run an STR similarity search on this cell line
Publications

PubMed=1262041; DOI=10.1007/BF02796440
Baldwin H. Tom, Lynne P. Rutzky, Milda M. Jakstys, Ryoichi Oyasu, Celia I. Kaye, Barry Donald Kahan;
Human colonic adenocarcinoma cells. I. Establishment and description of a new line.
In Vitro 12:180-191(1976)

Patent=US4228236
Milda M. Jakstys, Baldwin H. Tom, Barry Donald Kahan;
Process of producing carcinoembryonic antigen.
Patent number US4228236, 14-Oct-1980

PubMed=7370982
Lynne P. Rutzky, Celia I. Kaye, Michael Joseph Siciliano, Margaret Chao, Barry Donald Kahan;
Longitudinal karyotype and genetic signature analysis of cultured human colon adenocarcinoma cell lines LS180 and LS174T.
Cancer Res. 40:1443-1448(1980)

PubMed=6652615; DOI=10.1016/0165-4608(83)90092-4
Tchaw-Ren Chen, Robert J. Hay, Marvin L. Macy;
Intercellular karyotypic similarity in near-diploid cell lines of human tumor origins.
Cancer Genet. Cytogenet. 10:351-362(1983)

PubMed=9515795
Andrew B. Sparks, Patrice J. Morin, Bert Vogelstein, Kenneth Wayne Kinzler;
Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer.
Cancer Res. 58:1130-1134(1998)

PubMed=10737795; DOI=10.1073/pnas.97.7.3352; PMCID=PMC16243
Andrew J. Rowan, Hanan Lamlum, Mohammad Ilyas, James M.D. Wheeler, Jannes Straub, Angeliki Papadopoulou, David C. Bicknell, Walter Fred Bodmer, Ian Philip Mark Tomlinson;
APC mutations in sporadic colorectal tumors: a mutational 'hotspot' and interdependence of the 'two hits'.
Proc. Natl. Acad. Sci. U.S.A. 97:3352-3357(2000)

PubMed=11314036; DOI=10.1038/sj.onc.1204211
Eva Forgacs, Jonathan D. Wren, Craig Kamibayashi, Masashi Kondo, Xie L. Xu, Sanford David Markowitz, Gail E. Tomlinson, Carolyn Y. Muller, Adi F. Gazdar, Harold Ray Garner, John D. Minna;
Searching for microsatellite mutations in coding regions in lung, breast, ovarian and colorectal cancers.
Oncogene 20:1005-1009(2001)

PubMed=12615714
Paula M. Hempen, Lin Zhang, Ravi K. Bansal, Christine A. Iacobuzio-Donahue, Kathleen M. Murphy, Anirban Maitra, Bert Vogelstein, Robert H. Whitehead, Sanford David Markowitz, James K.V. Willson, Charles J. Yeo ...Show all 13 authors... , Ralph H. Hruban, Scott E. Kern; Show fewer authors
Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers.
Cancer Res. 63:994-999(2003)

PubMed=16418264; DOI=10.1073/pnas.0510146103; PMCID=PMC1327731
Ying Liu, Walter Fred Bodmer;
Analysis of p53 mutations and their expression in 56 colorectal cancer cell lines.
Proc. Natl. Acad. Sci. U.S.A. 103:976-981(2006)

PubMed=18258742; DOI=10.1073/pnas.0712176105; PMCID=PMC2268141
Muhammad Emaduddin, David C. Bicknell, Walter Fred Bodmer, Stephan M. Feller;
Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells.
Proc. Natl. Acad. Sci. U.S.A. 105:2358-2362(2008)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
S. Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera ...Show all 22 authors... , Rui Wang, Angela Tam, Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=20570890; DOI=10.1158/0008-5472.CAN-10-0192; PMCID=PMC2943514
Manickam Janakiraman, Efsevia Vakiani, Zhao-Shi Zeng, Christine A. Pratilas, Barry Stephen Taylor, Dhananjay Chitale, Ensar Halilovic, Manda Wilson, Kety Huberman, Julio Cezar Marques Ricarte Filho, Yogindra Persaud ...Show all 21 authors... , Douglas A. Levine, James Alexander Fagin, Suresh C. Jhanwar, John M. Mariadason, Alex Lash, Marc Ladanyi, Leonard B. Saltz, Adriana Heguy, Philip B. Paty, David B. Solit; Show fewer authors
Genomic and biological characterization of exon 4 KRAS mutations in human cancer.
Cancer Res. 70:5901-5911(2010)

PubMed=20606684; DOI=10.1038/sj.bjc.6605780; PMCID=PMC2920028
Karin Bracht, Angela M. Nicholls, Ying Liu, Walter Fred Bodmer;
5-fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency.
Br. J. Cancer 103:340-346(2010)

PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027
Jordi Ginesta Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A. Margolin, Sungjoon Kim, Christopher J. Wilson, Joseph Lehar, Gregory V. Kryukov, Dmitriy Sonkin, Anupama Reddy ...Show all 61 authors... , Manway Liu, Lauren Murray, Michael F. Berger, John E. Monahan, Paula Morais, Jodi Meltzer, Adam Korejwa, Judit Jane-Valbuena, Felipa A. Mapa, Joseph Thibault, Eva Bric-Furlong, Pichai Raman, Aaron Shipway, Ingo H. Engels, Jill Cheng, Guo-Ying K. Yu, Jian-Jun Yu, Peter Aspesi Jr., Melanie de Silva, Kalpana Jagtap, Michael D. Jones, Li Wang, Charles Hatton, Emanuele Palescandolo, Supriya Gupta, Scott Mahan, Carrie Sougnez, Robert C. Onofrio, Ted Liefeld, Laura E. MacConaill, Wendy Winckler, Michael Reich, Nan-Xin Li, Jill P. Mesirov, Stacey B. Gabriel, Gad Getz, Kristin Ardlie, Vivien Chan, Vic E. Myer, Barbara L. Weber, Jeff Porter, Markus Warmuth, Peter Finan, Jennifer L. Harris, Matthew Langer Meyerson, Todd Robert Golub, Michael P. Morrissey, William Raj Sellers, Robert Schlegel, Levi Alexander Garraway; Show fewer authors
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=23272949; DOI=10.1186/1755-8794-5-66; PMCID=PMC3543849
Andreas Schlicker, Garry Beran, Christine M. Chresta, Gael McWalter, Alison Pritchard, Susie Weston, Sarah Runswick, Sara Davenport, Kerry Heathcote, Denis Alferez Castro, George Orphanides ...Show all 13 authors... , Tim French, Lodewyk F.A. Wessels; Show fewer authors
Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines.
BMC Med. Genomics 5:66.1-66.15(2012)

PubMed=24755471; DOI=10.1158/0008-5472.CAN-14-0013
Dmitri Mouradov, Clare Sloggett, Robert N. Jorissen, Christopher G. Love, Shan Li, Antony Wilks Burgess, Diego Arango, Robert L. Strausberg, Daniel Buchanan, Samuel Wormald, Liam O'Connor ...Show all 17 authors... , Jennifer L. Wilding, David C. Bicknell, Ian Philip Mark Tomlinson, Walter Fred Bodmer, John M. Mariadason, Oliver M. Sieber; Show fewer authors
Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.
Cancer Res. 74:3238-3247(2014)

PubMed=25485619; DOI=10.1038/nbt.3080
Christiaan Klijn, Steffen Durinck, Eric W. Stawiski, Peter M. Haverty, Zhao-Shi Jiang, Han-Bin Liu, Jeremiah Degenhardt, Oleg Mayba, Florian Gnad, Jin-Feng Liu, Gregoire Pau ...Show all 30 authors... , Jens Reeder, Yi Cao, Kiran Mukhyala, Suresh K. Selvaraj, Ma-Mie Yu, Gregory J. Zynda, Matthew J. Brauer, Thomas D. Wu, Robert Clifford Gentleman, Gerard Manning, Robert L. Yauch, Richard Bourgon, David Stokoe, Zora Modrusan, Richard M. Neve, Frederic J. de Sauvage, Jeffrey Settleman, Somasekar Seshagiri, Ze-Min Zhang; Show fewer authors
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=25877200; DOI=10.1038/nature14397
Ma-Mie Yu, Suresh K. Selvaraj, May M.Y. Liang-Chu, Sahar Aghajani, Matthew Busse, Jean Yuan, Genee Lee, Franklin V. Peale, Christiaan Klijn, Richard Bourgon, Joshua S. Kaminker, Richard M. Neve;
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

PubMed=25926053; DOI=10.1038/ncomms8002
Enzo Medico, Mariangela Russo, Gabriele Picco, Carlotta Cancelliere, Emanuele Valtorta, Giorgio Corti, Michela Buscarino, Claudio Isella, Simona Lamba, Barbara Martinoglio, Silvio Veronese ...Show all 19 authors... , Salvatore Siena, Andrea Sartore-Bianchi, Marco Beccuti, Marcella Mottolese, Michael Linnebacher, Francesca Cordero, Federica Di Nicolantonio, Alberto Bardelli; Show fewer authors
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Jelle Scholtalbers, Sebastian Boegel, Thomas Bukur, Marius Byl, Sebastian Goerges, Patrick Sorn, Martin Loewer, Ugur Sahin, John C. Castle;
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=26537799; DOI=10.1074/mcp.M115.051235; PMCID=PMC4762531
Stephanie Holst, Anna J.M. Deuss, Gabi W. van Pelt, Sandra Johanna van Vliet, Juan J. Garcia-Vallejo, Carolien A.M. Koeleman, Andre M. Deelder, Wilma E. Mesker, Rob A.E.M. Tollenaar, Yoann Rombouts, Manfred Wuhrer;
N-glycosylation profiling of colorectal cancer cell lines reveals association of fucosylation with differentiation and caudal type homebox 1 (CDX1)/villin mRNA expression.
Mol. Cell. Proteomics 15:124-140(2016)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469
Francesco Iorio, Theo A. Knijnenburg, Daniel J. Vis, Graham Robert Bignell, Michael Patrick Menden, Michael Schubert, Nanne Aben, Emanuel Goncalves, Syd Barthorpe, Howard Lightfoot, Thomas Cokelaer ...Show all 39 authors... , Patricia Greninger, Ewald van Dyk, Han Chang, Heshani de Silva, Holger Heyn, Xian-Ming Deng, Regina K. Egan, Qing-Song Liu, Tatiana Mironenko, Xeni Mitropoulos, Laura Richardson, Jin-Hua Wang, Ting-Hu Zhang, Sebastian Moran, Sergi Sayols, Maryam Soleimani, David Tamborero, Nuria Lopez-Bigas, Petra Ross-Macdonald, Manel Esteller, Nathanael S. Gray, Daniel Arie Haber, Michael Rudolf Stratton, Cyril Henri Benes, Lodewyk F.A. Wessels, Julio Saez-Rodriguez, Ultan McDermott, Mathew J. Garnett; Show fewer authors
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28854368; DOI=10.1016/j.celrep.2017.08.010; PMCID=PMC5583477
Theodoros I. Roumeliotis, Steven P. Williams, Emanuel Goncalves, Clara Alsinet, Martin Del Castillo Velasco-Herrera, Nanne Aben, Fatemeh Zamanzad Ghavidel, Magali Michaut, Michael Schubert, Stacey Price, James C. Wright ...Show all 24 authors... , Lu Yu, Mi Yang, Rodrigo Dienstmann, Justin H. Guinney, Pedro Beltrao, Alvis Brazma, Mercedes Pardo, Oliver Stegle, David J. Adams, Lodewyk F.A. Wessels, Julio Saez-Rodriguez, Ultan McDermott, Jyoti S. Choudhary; Show fewer authors
Genomic determinants of protein abundance variation in colorectal cancer cells.
Cell Rep. 20:2201-2214(2017)

PubMed=29101300; DOI=10.15252/msb.20177701; PMCID=PMC5731344
Martin Frejno, Riccardo Zenezini Chiozzi, Mathias Wilhelm, Heiner Koch, Run-Sheng Zheng, Susan Klaeger, Benjamin Ruprecht, Chen Meng, Karl Kramer, Anna Jarzab, Stephanie Heinzlmeir ...Show all 20 authors... , Elaine Johnstone, Enric Domingo, David James Kerr, Moritz Jesinghaus, Julia Slotta-Huspenina, Wilko Weichert, Stefan Knapp, Stephan M. Feller, Bernhard Kuster; Show fewer authors
Pharmacoproteomic characterisation of human colon and rectal cancer.
Mol. Syst. Biol. 13:951-951(2017)

PubMed=29444439; DOI=10.1016/j.celrep.2018.01.051; PMCID=PMC6343826
Tina L. Yuan, Arnaud Amzallag, Rachel Bagni, Ming Yi, Shervin Afghani, William Burgan, Nicole Fer, Leslie A. Strathern, Katie Powell, Brian Smith, Andrew Michael Waters ...Show all 30 authors... , David Alan Drubin, Ty Thomson, Rosy Liao, Patricia Greninger, Giovanna T. Stein, Ellen Murchie, Eliane Cortez, Regina K. Egan, Lauren Procter, Matthew Bess, Kwong Tai Cheng, Chih-Shia Lee, Liam Changwoo Lee, Christof Fellmann, Robert Stephens, Ji Luo, Scott William Lowe, Cyril Henri Benes, Frank McCormick; Show fewer authors
Differential effector engagement by oncogenic KRAS.
Cell Rep. 22:1889-1902(2018)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=30971826; DOI=10.1038/s41586-019-1103-9
Fiona M. Behan, Francesco Iorio, Gabriele Picco, Emanuel Goncalves, Charlotte M. Beaver, Giorgia Migliardi, Rita Santos, Yanhua Rao, Francesco Sassi, Marika Pinnelli, Rizwan Ansari ...Show all 25 authors... , Sarah Harper, David Adam Jackson, Rebecca McRae, Rachel Pooley, Piers Wilkinson, Dieudonne J. van der Meer, David Dow, Carolyn A. Buser-Doepner, Andrea Bertotti, Livio Trusolino, Euan Alexander Stronach, Julio Saez-Rodriguez, Kosuke Yusa, Mathew J. Garnett; Show fewer authors
Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.
Nature 568:511-516(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Mahmoud Ghandi, Franklin W. Huang, Judit Jane-Valbuena, Gregory V. Kryukov, Christopher C. Lo, E. Robert McDonald 3rd, Jordi Ginesta Barretina, Ellen T. Gelfand, Craig M. Bielski, Hao-Xin Li, Kevin Hu ...Show all 68 authors... , Alexander Y. Andreev-Drakhlin, Jaegil Kim, Julian M. Hess, Brian J. Haas, Francois Aguet, Barbara A. Weir, Michael V. Rothberg, Brenton R. Paolella, Michael Scott Lawrence, Rehan Akbani, Yi-Ling Lu, Hong L. Tiv, Prafulla C. Gokhale, Antoine de Weck, Ali Amin Mansour, Coyin Oh, Juliann Shih, Kevin Hadi, Yanay Rosen, Jonathan Bistline, Kavitha Venkatesan, Anupama Reddy, Dmitriy Sonkin, Manway Liu, Joseph Lehar, Joshua M. Korn, Dale A. Porter, Michael D. Jones, Javad Golji, Giordano Caponigro, Jordan E. Taylor, Caitlin M. Dunning, Amanda L. Creech, Allison C. Warren, James M. McFarland, Mahdi Zamanighomi, Audrey Kauffmann, Nicolas Stransky, Marcin Imielinski, Yosef E. Maruvka, Andrew D. Cherniack, Aviad Tsherniak, Francisca Vazquez, Jacob D. Jaffe, Andrew Alan Lane, David M. Weinstock, Cory M. Johannessen, Michael P. Morrissey, Frank Stegmeier, Robert Schlegel, William Chun Hahn, Gad Getz, Gordon B. Mills, Jesse S. Boehm, Todd Robert Golub, Levi Alexander Garraway, William Raj Sellers; Show fewer authors
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Cross-references
Cell line collections (Providers) AddexBio; C0009006/56
ATCC; CCL-187 - Discontinued
ATCC; CL-187
BCRC; 60100
ECACC; 87021202
ICLC; HTL01016
IZSLER; BS TCL 82
NCBI_Iran; C508
Cell line databases/resources CLO; CLO_0007394
CLO; CLO_0007404
MCCL; MCC:0000291
CLDB; cl3262
CLDB; cl3263
CLDB; cl7120
cancercelllines; CVCL_0397
CCRID; 1101HUM-PUMC000284
Cell_Model_Passport; SIDM00680
ColonAtlas; LS180
Cosmic-CLP; 998189
DepMap; ACH-000957
LINCS_LDP; LCL-1183
Lonza; 348
Anatomy/cell type resources BTO; BTO_0001609
Biological sample resources BioSample; SAMN03472231
BioSample; SAMN10988327
CRISP screens repositories BioGRID_ORCS_Cell_line; 564
Chemistry resources ChEMBL-Cells; CHEMBL4295398
ChEMBL-Targets; CHEMBL4296462
GDSC; 998189
PharmacoDB; LS180_859_2019
PubChem_Cell_line; CVCL_0397
Encyclopedic resources Wikidata; Q54903057
Experimental variables resources EFO; EFO_0006640
Gene expression databases ArrayExpress; E-MTAB-2706
ArrayExpress; E-MTAB-2770
ArrayExpress; E-MTAB-3610
GEO; GSM206520
GEO; GSM513928
GEO; GSM514299
GEO; GSM741271
GEO; GSM784017
GEO; GSM827346
GEO; GSM887279
GEO; GSM888354
GEO; GSM1346847
GEO; GSM1374634
GEO; GSM1374635
GEO; GSM1374636
GEO; GSM1448139
GEO; GSM1670060
Metabolomic databases MetaboLights; MTBLS227
Polymorphism and mutation databases Cosmic; 869793
Cosmic; 913893
Cosmic; 948854
Cosmic; 995378
Cosmic; 1043820
Cosmic; 1184098
Cosmic; 1187311
Cosmic; 1466819
Cosmic; 1479574
Cosmic; 1708417
Cosmic; 2052595
Cosmic; 2301998
Cosmic; 2667976
Cosmic; 2727472
IARC_TP53; 21766
LiGeA; CCLE_023
Progenetix; CVCL_0397
Proteomic databases PRIDE; PXD005235
PRIDE; PXD005354
PRIDE; PXD005355
PRIDE; PXD030304
Sequence databases EGA; EGAS00001000610
EGA; EGAS00001000978
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number47