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Cellosaurus CellSensor CYP1A1-bla LS-180 (CVCL_KS51)

[Text version]
Cell line name CellSensor CYP1A1-bla LS-180
Synonyms CYP1A1-bla LS-180
Accession CVCL_KS51
Resource Identification Initiative To cite this cell line use: CellSensor CYP1A1-bla LS-180 (RRID:CVCL_KS51)
Comments Population: Caucasian.
Characteristics: Transfected with a plasmid containing a beta-lactamase reporter gene under control of the CYP1A1 promoter.
Genetic integration: Method=Transfection; Gene=UniProtKB; P33967; Bacillus cereus Bsr.
Genetic integration: Method=Transfection; Gene=UniProtKB; P62593; Escherichia coli beta-lactamase bla (Note=With p.Met1_Phe22del, p.Ala23Met, p.Val82Ile and p.Met184Val).
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Cell type: Epithelial cell of colon; CL=CL_0011108.
Sequence variations
  • Mutation; HGNC; HGNC:173; ACVR2A; Simple; p.Lys437Argfs*5 (c.1310delA); dbSNP=rs764719749; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser45Phe (c.134C>T); ClinVar=VCV000017588; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11773; TGFBR2; Simple; p.Lys128Serfs*35 (c.383delA); ClinVar=VCV000477546; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0397 (LS180)
Sex of cell Female
Age at sampling 58Y
Category Cancer cell line
Web pages Provider; Thermo Fisher; K1678; https://www.thermofisher.com/order/catalog/product/K1678
Cross-references
Cell line databases/resources cancercelllines; CVCL_KS51
Encyclopedic resources Wikidata; Q54809176
Entry history
Entry creation22-Aug-2017
Last entry update14-Aug-2025
Version number16