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Cellosaurus IEC-6 (CVCL_0343)

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Cell line name IEC-6
Synonyms IEC 6; IEC6; Intestinal Epithelioid Cell line No. 6
Accession CVCL_0343
Resource Identification Initiative To cite this cell line use: IEC-6 (RRID:CVCL_0343)
Comments Senescence: Capable of at least 10 PDL.
Doubling time: ~20 hours (PubMed=88453); ~50 hours (DSMZ=ACC-111).
Derived from site: In situ; Small intestine; UBERON=UBERON_0002108.
Cell type: Epithelial cell of intestine; CL=CL_0002563.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Charles River Sprague Dawley (CD(SD)); RS=RS_0000695.
Hierarchy Children:
CVCL_F4QA (HyCyte IEC-6 stable cell line for rAcsf2 overexpression)CVCL_F4RD (HyCyte IEC-6 stable cell line for rRac2 overexpression)CVCL_6973 (IEC-CF7)
CVCL_A5RH (IEC6-Cdx2L1)CVCL_A5RI (IEC6-Cdx2L2)CVCL_A5RJ (IEC6-Cdx2MT15)
Sex of cell Male
Age at sampling 18-24D
Category Finite cell line
Web pages Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/i/cell-lines-detail-606.html
Publications

PubMed=88453; DOI=10.1083/jcb.80.2.248; PMCID=PMC2110349
Andrea Quaroni, Jack Raymond Wands, Robert L. Trelstad, Kurt Julius Isselbacher;
Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteria.
J. Cell Biol. 80:248-265(1979)

PubMed=7681632; DOI=10.1152/ajplung.1993.264.3.L229
Jan Bijman, Wilfried Dalemans, Maarten Kansen, Joke Keulemans, Elly Verbeek, Andre T. Hoogeveen, Hugo De Jonge, Martina Wilke, Dominique Dreyer, Jean-Pierre Lecocq, Andrea Pavirani, Bob J. Scholte;
Low-conductance chloride channels in IEC-6 and CF nasal cells expressing CFTR.
Am. J. Physiol. 264:L229-L235(1993)

PubMed=8552090; DOI=10.1128/mcb.16.2.619; PMCID=PMC231041
Eunran Suh, Peter George Traber;
An intestine-specific homeobox gene regulates proliferation and differentiation.
Mol. Cell. Biol. 16:619-625(1996)

PubMed=11925460; DOI=10.1093/jn/132.4.680
Carla Thomas, Phillip S. Oates;
IEC-6 cells are an appropriate model of intestinal iron absorption in rats.
J. Nutr. 132:680-687(2002)

PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040
Dieter C. Gruenert, Marjolaine Willems, Jean-Jacques Cassiman, Raymond A. Frizzell;
Established cell lines used in cystic fibrosis research.
J. Cyst. Fibros. 3:191-196(2004)

Cross-references
Cell line collections (Providers) AddexBio; P0021001/81
ATCC; CRL-1592
BCRC; 60301
BCRJ; 0117
CLS; 302149
DSMZ; ACC-111
ECACC; 88071401
IZSLER; BS CL 117
KCB; KCB 200720YJ
KCLB; 21592
RCB; RCB0993
Cell line databases/resources CLO; CLO_0004342
CLO; CLO_0050826
MCCL; MCC:0000239
CLDB; cl1802
CLDB; cl1803
CLDB; cl5209
CCRID; 1101RAT-PUMC000110
DSMZCellDive; ACC-111
Lonza; 980
Anatomy/cell type resources BTO; BTO_0001497
Chemistry resources ChEMBL-Cells; CHEMBL4295425
ChEMBL-Targets; CHEMBL4296440
PubChem_Cell_line; CVCL_0343
Encyclopedic resources Wikidata; Q54897315
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number26