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Cellosaurus IEC-CF7 (CVCL_6973)

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Cell line name IEC-CF7
Accession CVCL_6973
Resource Identification Initiative To cite this cell line use: IEC-CF7 (RRID:CVCL_6973)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1884; CFTR.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Small intestine; UBERON=UBERON_0002108.
Cell type: Epithelial cell of intestine; CL=CL_0002563.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Charles River Sprague Dawley (CD(SD)); RS=RS_0000695.
Hierarchy Parent: CVCL_0343 (IEC-6)
Sex of cell Male
Age at sampling 18-24D
Category Finite cell line
Publications

PubMed=7681632; DOI=10.1152/ajplung.1993.264.3.L229
Jan Bijman, Wilfried Dalemans, Maarten Kansen, Joke Keulemans, Elly Verbeek, Andre T. Hoogeveen, Hugo De Jonge, Martina Wilke, Dominique Dreyer, Jean-Pierre Lecocq, Andrea Pavirani, Bob J. Scholte;
Low-conductance chloride channels in IEC-6 and CF nasal cells expressing CFTR.
Am. J. Physiol. 264:L229-L235(1993)

PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040
Dieter C. Gruenert, Marjolaine Willems, Jean-Jacques Cassiman, Raymond A. Frizzell;
Established cell lines used in cystic fibrosis research.
J. Cyst. Fibros. 3:191-196(2004)

Cross-references
Anatomy/cell type resources BTO; BTO_0002579
Encyclopedic resources Wikidata; Q54897316
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number15