ID   IEC-6
AC   CVCL_0343
SY   IEC 6; IEC6; Intestinal Epithelioid Cell line No. 6
DR   BTO; BTO:0001497
DR   CLO; CLO_0004342
DR   CLO; CLO_0050826
DR   MCCL; MCC:0000239
DR   CLDB; cl1802
DR   CLDB; cl1803
DR   CLDB; cl5209
DR   AddexBio; P0021001/81
DR   ATCC; CRL-1592
DR   BCRC; 60301
DR   BCRJ; 0117
DR   CCRID; 1101RAT-PUMC000110
DR   ChEMBL-Cells; CHEMBL4295425
DR   ChEMBL-Targets; CHEMBL4296440
DR   DSMZ; ACC-111
DR   DSMZCellDive; ACC-111
DR   ECACC; 88071401
DR   KCB; KCB 200720YJ
DR   KCLB; 21592
DR   Lonza; 980
DR   PubChem_Cell_line; CVCL_0343
DR   RCB; RCB0993
DR   Wikidata; Q54897315
RX   PubMed=88453;
RX   PubMed=7681632;
RX   PubMed=8552090;
RX   PubMed=11925460;
RX   PubMed=15463957;
CC   Senescence: Capable of at least 10 PDL.
CC   Doubling time: ~20 hours (PubMed=88453); ~50 hours (DSMZ=ACC-111).
CC   Derived from site: In situ; Small intestine; UBERON=UBERON_0002108.
CC   Cell type: Epithelial cell of intestine; CL=CL_0002563.
CC   Breed/subspecies: Charles River Sprague Dawley (CD(SD)).
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
SX   Male
AG   18-24D
CA   Finite cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 23
RX   PubMed=88453; DOI=10.1083/jcb.80.2.248;
RA   Quaroni A., Wands J.R., Trelstad R.L., Isselbacher K.J.;
RT   "Epithelioid cell cultures from rat small intestine. Characterization
RT   by morphologic and immunologic criteria.";
RL   J. Cell Biol. 80:248-265(1979).
RX   PubMed=7681632; DOI=10.1152/ajplung.1993.264.3.L229;
RA   Bijman J., Dalemans W., Kansen M., Keulemans J., Verbeek E.,
RA   Hoogeveen A.T., De Jonge H., Wilke M., Dreyer D., Lecocq J.-P.,
RA   Pavirani A., Scholte B.J.;
RT   "Low-conductance chloride channels in IEC-6 and CF nasal cells
RT   expressing CFTR.";
RL   Am. J. Physiol. 264:L229-L235(1993).
RX   PubMed=8552090; DOI=10.1128/mcb.16.2.619;
RA   Suh E., Traber P.G.;
RT   "An intestine-specific homeobox gene regulates proliferation and
RT   differentiation.";
RL   Mol. Cell. Biol. 16:619-625(1996).
RX   PubMed=11925460; DOI=10.1093/jn/132.4.680;
RA   Thomas C., Oates P.S.;
RT   "IEC-6 cells are an appropriate model of intestinal iron absorption in
RT   rats.";
RL   J. Nutr. 132:680-687(2002).
RX   PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040;
RA   Gruenert D.C., Willems M., Cassiman J.-J., Frizzell R.A.;
RT   "Established cell lines used in cystic fibrosis research.";
RL   J. Cyst. Fibros. 3:191-196(2004).