Cellosaurus logo
expasy logo

Cellosaurus A549L0 (CVCL_ZX73)

[Text][XML][JSON]
Cell line name A549L0
Accession CVCL_ZX73
Resource Identification Initiative To cite this cell line use: A549L0 (RRID:CVCL_ZX73)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Children:
CVCL_ZX74 (A549L6)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=26090868; DOI=10.18632/oncotarget.4416; PMCID=PMC4673208
Xiao-Pan Cai, Jian Luo, Xing-Hai Yang, Hua-Yun Deng, Ji-Shen Zhang, Shi-Chang Li, Hai-Feng Wei, Cheng Yang, Le-Qin Xu, Rong-Rong Jin, Zhen-Xi Li ...Show all 19 authors... , Wang Zhou, Jian-Dong Ding, Jian-Jun Chu, Lian-Shun Jia, Qi Jia, Cheng-Jun Tan, Ming-Yao Liu, Jian-Ru Xiao; Show fewer authors
In vivo selection for spine-derived highly metastatic lung cancer cells is associated with increased migration, inflammation and decreased adhesion.
Oncotarget 6:22905-22917(2015)

Patent=CN103756968B
Jian Luo, Jian-Ru Xiao, Ming-Yao Liu, Xiao-Pan Cai;
Spinal highly-metastatic human lung adenocarcinoma cell strain and construction process thereof and application.
Patent number CN103756968B, 20-Jan-2016

Cross-references
Cell line databases/resources cancercelllines; CVCL_ZX73
Encyclopedic resources Wikidata; Q102113491
Entry history
Entry creation29-Oct-2020
Last entry update14-Aug-2025
Version number9