ID   A549L0
AC   CVCL_ZX73
DR   cancercelllines; CVCL_ZX73
DR   Wikidata; Q102113491
RX   Patent=CN103756968B;
RX   PubMed=26090868;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: UniProtKB; P08659; Firefly luciferase.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0023 ! A-549
SX   Male
AG   58Y
CA   Cancer cell line
DT   Created: 29-10-20; Last updated: 05-10-23; Version: 6
//
RX   Patent=CN103756968B;
RA   Luo J., Xiao J.-R., Liu M.-Y., Cai X.-P.;
RT   "Spinal highly-metastatic human lung adenocarcinoma cell strain and
RT   construction process thereof and application.";
RL   Patent number CN103756968B, 20-Jan-2016.
//
RX   PubMed=26090868; DOI=10.18632/oncotarget.4416;
RA   Cai X.-P., Luo J., Yang X.-H., Deng H.-Y., Zhang J.-S., Li S.-C.,
RA   Wei H.-F., Yang C., Xu L.-Q., Jin R.-R., Li Z.-X., Zhou W., Ding J.-D.,
RA   Chu J.-J., Jia L.-S., Jia Q., Tan C.-J., Liu M.-Y., Xiao J.-R.;
RT   "In vivo selection for spine-derived highly metastatic lung cancer
RT   cells is associated with increased migration, inflammation and
RT   decreased adhesion.";
RL   Oncotarget 6:22905-22917(2015).
//