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Cellosaurus OSA 1777 (CVCL_ZV94)

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Cell line name OSA 1777
Accession CVCL_ZV94
Resource Identification Initiative To cite this cell line use: OSA 1777 (RRID:CVCL_ZV94)
Comments Problematic cell line: Contaminated. Shown to be a SYO-1 derivative (PubMed=40772425). Originally thought to originate from a 19 year old female patient with a proximal femus osteosarcoma.
Population: Japanese.
Doubling time: ~60 hours (PubMed=31736134).
Derived from site: In situ; Groin; UBERON=UBERON_0008337.
Sequence variations
  • Gene fusion; HGNC; HGNC:11340; SS18 + HGNC; HGNC:11336; SSX2; Name(s)=SS18-SSX2 (from parent cell line).
  • Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Gly34Val (c.101G>T); ClinVar=VCV000017582; Zygosity=Unspecified (from parent cell line).
Disease Biphasic synovial sarcoma (NCIt: C4279)
Synovial sarcoma (ORDO: Orphanet_3273)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7146 (SYO-1)
Sex of cell Female
Age at sampling 19Y
Category Cancer cell line
STR profile Source(s): PubMed=31736134

Markers:
AmelogeninX
CSF1PO10
D3S135815
D5S8189,12
D7S82011
D8S117912,24
D13S3179
D16S5399,13
D18S5115,19
D21S1130
FGA19,24
Penta D9,12
Penta E5,15
TH016,7
TPOX9,12
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=31736134; DOI=10.1002/jor.24528
Pichaya Thanindratarn, Xiao-Yang Li, Dylan C. Dean, Scott D. Nelson, Francis John Hornicek, Zhen-Feng Duan;
Establishment and characterization of a recurrent osteosarcoma cell line: OSA 1777.
J. Orthop. Res. 38:902-910(2020)

PubMed=40772425; DOI=10.1002/jor.70025
Pichaya Thanindratarn, Xiao-Yang Li, Dylan C. Dean, Scott D. Nelson, Francis John Hornicek, Zhen-Feng Duan;
Retraction to 'Establishment and characterization of a recurrent osteosarcoma cell line: OSA 1777'.
J. Orthop. Res. 43:1887-1887(2025)

Cross-references
Encyclopedic resources Wikidata; Q98128380
Entry history
Entry creation02-Jul-2020
Last entry update14-Aug-2025
Version number5