ID   OSA 1777
AC   CVCL_ZV94
DR   Wikidata; Q98128380
RX   PubMed=31736134;
RX   PubMed=40772425;
CC   Problematic cell line: Contaminated. Shown to be a SYO-1 derivative (PubMed=40772425). Originally thought to originate from a 19 year old female patient with a proximal femus osteosarcoma.
CC   Population: Japanese.
CC   Doubling time: ~60 hours (PubMed=31736134).
CC   Sequence variation: Gene fusion; HGNC; HGNC:11340; SS18 + HGNC; HGNC:11336; SSX2; Name(s)=SS18-SSX2 (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Gly34Val (c.101G>T); ClinVar=VCV000017582; Zygosity=Unspecified (from parent cell line).
CC   Derived from site: In situ; Groin; UBERON=UBERON_0008337.
ST   Source(s): PubMed=31736134
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 9
ST   D16S539: 9,13
ST   D18S51: 15,19
ST   D21S11: 30
ST   D3S1358: 15
ST   D5S818: 9,12
ST   D7S820: 11
ST   D8S1179: 12,24
ST   FGA: 19,24
ST   Penta D: 9,12
ST   Penta E: 5,15
ST   TH01: 6,7
ST   TPOX: 9,12
ST   vWA: 17
DI   NCIt; C4279; Biphasic synovial sarcoma
DI   ORDO; Orphanet_3273; Synovial sarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_7146 ! SYO-1
SX   Female
AG   19Y
CA   Cancer cell line
DT   Created: 02-07-20; Last updated: 14-08-25; Version: 5
//
RX   PubMed=31736134; DOI=10.1002/jor.24528;
RA   Thanindratarn, Pichaya
RA   Li, Xiao-Yang
RA   Dean, Dylan C.
RA   Nelson, Scott D.
RA   Hornicek, Francis John
RA   Duan, Zhen-Feng
RT   "Establishment and characterization of a recurrent osteosarcoma cell
RT   line: OSA 1777.";
RL   J. Orthop. Res. 38:902-910(2020).
//
RX   PubMed=40772425; DOI=10.1002/jor.70025;
RA   Thanindratarn, Pichaya
RA   Li, Xiao-Yang
RA   Dean, Dylan C.
RA   Nelson, Scott D.
RA   Hornicek, Francis John
RA   Duan, Zhen-Feng
RT   "Retraction: Establishment and characterization of a recurrent
RT   osteosarcoma cell line: OSA 1777.";
RL   J. Orthop. Res. 0:0-0(2025).
//