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Cellosaurus Y79-Luc (CVCL_ZF06)

[Text version]
Cell line name Y79-Luc
Accession CVCL_ZF06
Resource Identification Initiative To cite this cell line use: Y79-Luc (RRID:CVCL_ZF06)
Comments Population: Caucasian.
Characteristics: Expression of luciferase is under the control of the CMV promoter.
Transfected with: UniProtKB; P08659; Firefly luciferase.
Derived from site: In situ; Eye, globe; UBERON=UBERON_0010230.
Sequence variations
  • Mutation; HGNC; 9884; RB1; Unexplicit; Ex2-6del; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9884; RB1; Unexplicit; IVS20+1G>A; Zygosity=Heterozygous (from parent cell line).
Disease Retinoblastoma (NCIt: C7541)
Retinoblastoma (ORDO: Orphanet_790)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1893 (Y-79)
Sex of cell Female
Age at sampling 2Y6M
Category Cancer cell line

PubMed=27050416; DOI=10.1371/journal.pone.0153011
Ferrario A., Luna M., Rucker N., Wong S., Lederman A., Kim J., Gomer C.
Targeting survivin enhances chemosensitivity in retinoblastoma cells and orthotopic tumors.
PLoS ONE 11:E0153011-E0153011(2016)

Encyclopedic resources Wikidata; Q98136368
Entry history
Entry creation02-Jul-2020
Last entry update29-Jun-2023
Version number7