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Cellosaurus Y79-Luc (CVCL_ZF06)

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Cell line name Y79-Luc
Accession CVCL_ZF06
Resource Identification Initiative To cite this cell line use: Y79-Luc (RRID:CVCL_ZF06)
Comments Population: Caucasian.
Characteristics: Expression of luciferase is under the control of the CMV promoter.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Derived from site: In situ; Eye, globe; UBERON=UBERON_0010230.
Sequence variations
  • Mutation; HGNC; HGNC:9884; RB1; Unexplicit; Ex2-6del; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Unexplicit; IVS20+1G>A; Zygosity=Heterozygous (from parent cell line).
Disease Retinoblastoma (NCIt: C7541)
Retinoblastoma (ORDO: Orphanet_790)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1893 (Y-79)
Sex of cell Female
Age at sampling 2Y6M
Category Cancer cell line
Publications

PubMed=27050416; DOI=10.1371/journal.pone.0153011; PMCID=PMC4822873
Angela Ferrario, Marian C. Luna, Natalie Rucker, Sam Wong, Ariel Lederman, Jonathan Kim, Charles Joseph Gomer;
Targeting survivin enhances chemosensitivity in retinoblastoma cells and orthotopic tumors.
PLoS ONE 11:e0153011.1-e0153011.16(2016)

Cross-references
Encyclopedic resources Wikidata; Q98136368
Entry history
Entry creation02-Jul-2020
Last entry update14-Aug-2025
Version number10