ID   Y79-Luc
AC   CVCL_ZF06
DR   Wikidata; Q98136368
RX   PubMed=27050416;
CC   Population: Caucasian.
CC   Characteristics: Expression of luciferase is under the control of the CMV promoter.
CC   Sequence variation: Mutation; HGNC; HGNC:9884; RB1; Unexplicit; Ex2-6del; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9884; RB1; Unexplicit; IVS20+1G>A; Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
CC   Derived from site: In situ; Eye, globe; UBERON=UBERON_0010230.
DI   NCIt; C7541; Retinoblastoma
DI   ORDO; Orphanet_790; Retinoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1893 ! Y-79
SX   Female
AG   2Y6M
CA   Cancer cell line
DT   Created: 02-07-20; Last updated: 14-08-25; Version: 10
//
RX   PubMed=27050416; DOI=10.1371/journal.pone.0153011; PMCID=PMC4822873;
RA   Ferrario, Angela
RA   Luna, Marian C.
RA   Rucker, Natalie
RA   Wong, Sam
RA   Lederman, Ariel
RA   Kim, Jonathan
RA   Gomer, Charles Joseph
RT   "Targeting survivin enhances chemosensitivity in retinoblastoma cells
RT   and orthotopic tumors.";
RL   PLoS ONE 11:e0153011.1-e0153011.16(2016).
//