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Cellosaurus EDi001-B (CVCL_ZA47)

[Text version]
Cell line name EDi001-B
Synonyms AST18; AST18 iPS cells; Alpha-synuclein triplication 18
Accession CVCL_ZA47
Resource Identification Initiative To cite this cell line use: EDi001-B (RRID:CVCL_ZA47)
Comments From: University of Edinburgh; Edinburgh; United Kingdom.
Population: Caucasian.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Gene amplification; HGNC; HGNC:11138; SNCA; Triplication; Zygosity=Heterozygous (from parent cell line).
Disease Parkinson disease 4, autosomal dominant (NCIt: C198604)
Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_F204 (ND27760)
Children:
CVCL_A1XP (EDi001-B-1)CVCL_A1XQ (EDi001-B-2)CVCL_A1XR (EDi001-B-3)
CVCL_A1XS (EDi001-B-4)
Sex of cell Female
Age at sampling 55Y
Category Induced pluripotent stem cell
Publications

PubMed=21863007; DOI=10.1038/ncomms1453; PMCID=PMC3265381
Michael J. Devine, Mina Ryten, Petr Vodicka, Alison J. Thomson, Tom Burdon, Henry Houlden, Fatima Cavaleri, Masumi Nagano, Nicola Jane Drummond, Jan-Willem Taanman, Anthony Henry Vernon Schapira ...Show all 15 authors... , Katrina Ann Gwinn-Hardy, John Hardy, Patrick A. Lewis, Tilo Kunath; Show fewer authors
Parkinson's disease induced pluripotent stem cells with triplication of the alpha-synuclein locus.
Nat. Commun. 2:440.1-440.10(2011)

Cross-references
Cell line collections (Providers) EBiSC; EDi001-B
ECACC; 66770007 - Discontinued
Cell line databases/resources hPSCreg; EDi001-B
Biological sample resources BioSamples; SAMEA7111749
Encyclopedic resources Wikidata; Q98125938
Entry history
Entry creation02-Jul-2020
Last entry update19-Dec-2024
Version number10