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Cellosaurus EDi001-B-2 (CVCL_A1XQ)

[Text version]
Cell line name EDi001-B-2
Synonyms AST18-7B
Accession CVCL_A1XQ
Resource Identification Initiative To cite this cell line use: EDi001-B-2 (RRID:CVCL_A1XQ)
Comments From: University of Edinburgh; Edinburgh; United Kingdom.
Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; 11138; SNCA.
Derived from sampling site: Skin; dermis. Cell type=Fibroblast.
Disease Parkinson's disease (NCIt: C26845)
Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_ZA47 (EDi001-B)
Sex of cell Female
Age at sampling 55Y
Category Induced pluripotent stem cell

PubMed=30472757; DOI=10.1111/ejn.14286
Chen Y., Dolt K.S., Kriek M., Baker T., Downey P., Drummond N.J., Canham M.A., Natalwala A., Rosser S., Kunath T.
Engineering synucleinopathy-resistant human dopaminergic neurons by CRISPR-mediated deletion of the SNCA gene.
Eur. J. Neurosci. 49:510-524(2019)

Cell line collections ECACC; 66770009
Cell line databases/resources hPSCreg; EDi001-B-2
Biological sample resources BioSamples; SAMEA7111751
Encyclopedic resources Wikidata; Q105506812
Entry history
Entry creation12-Jan-2021
Last entry update21-Mar-2023
Version number5