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Cellosaurus 4a-3A (CVCL_Z622)

[Text version]
Cell line name 4a-3A
Synonyms 4A-3A; 4a3A
Accession CVCL_Z622
Resource Identification Initiative To cite this cell line use: 4a-3A (RRID:CVCL_Z622)
Comments Group: Insect cell line.
Group: Malaria research cell line.
Omics: Genomics; Whole genome sequencing.
Omics: Transcriptomics; RNAseq.
Species of origin Anopheles gambiae (African malaria mosquito) (NCBI Taxonomy: 7165)
Breed/subspecies: 4a r/r.
Originate from same individual CVCL_Z623 ! 4a-3B
Sex of cell Female
Age at sampling Neonate larva
Category Spontaneously immortalized cell line
Publications

PubMed=10206988; DOI=10.1074/jbc.274.17.11727
Muller H.-M., Dimopoulos G., Blass C., Kafatos F.C.
A hemocyte-like cell line established from the malaria vector Anopheles gambiae expresses six prophenoloxidase genes.
J. Biol. Chem. 274:11727-11735(1999)

PubMed=22375833; DOI=10.1186/1471-2180-12-S1-S11; PMCID=PMC3287508
Pinto S.B., Mariconti M., Bazzocchi C., Bandi C., Sinkins S.P.
Wolbachia surface protein induces innate immune responses in mosquito cells.
BMC Microbiol. 12 Suppl. 1:S11.1-S11.6(2012)

PubMed=23382679; DOI=10.1371/journal.ppat.1003145; PMCID=PMC3561300
Lombardo F., Ghani Y., Kafatos F.C., Christophides G.K.
Comprehensive genetic dissection of the hemocyte immune response in the malaria mosquito Anopheles gambiae.
PLoS Pathog. 9:e1003145.1-e1003145.11(2013)

PubMed=36514125; DOI=10.1186/s13071-022-05590-3; PMCID=PMC9749150
Eggleston H., Njoya K., Anderson C.E., Holm I., Eiglmeier K., Liang J.-T., Sharakhov I.V., Vernick K.D., Riehle M.M.
Molecular characterization and genetic authentication assay for Anopheles 'hemocyte-like' cell lines 4a-3A and 4a-3B.
Parasit. Vectors 15:465.1-465.13(2022)

Cross-references
Cell line collections (Providers) BEI_Resources; MRA-918 - Discontinued
Encyclopedic resources Wikidata; Q54603336
Entry history
Entry creation10-Apr-2015
Last entry update10-Apr-2025
Version number10