ID   4a-3A
AC   CVCL_Z622
SY   4A-3A; 4a3A
DR   BEI_Resources; MRA-918
DR   Wikidata; Q54603336
RX   PubMed=10206988;
RX   PubMed=22375833;
RX   PubMed=23382679;
RX   PubMed=36514125;
CC   Group: Insect cell line.
CC   Group: Malaria research cell line.
CC   Omics: Genomics; Whole genome sequencing.
CC   Omics: Transcriptomics; RNAseq.
CC   Discontinued: BEI_Resources; MRA-918; probable.
CC   Breed/subspecies: 4a r/r.
OX   NCBI_TaxID=7165; ! Anopheles gambiae (African malaria mosquito)
OI   CVCL_Z623 ! 4a-3B
SX   Female
AG   Neonate larva
CA   Spontaneously immortalized cell line
DT   Created: 10-04-15; Last updated: 10-04-25; Version: 10
//
RX   PubMed=10206988; DOI=10.1074/jbc.274.17.11727;
RA   Muller H.-M., Dimopoulos G., Blass C., Kafatos F.C.;
RT   "A hemocyte-like cell line established from the malaria vector
RT   Anopheles gambiae expresses six prophenoloxidase genes.";
RL   J. Biol. Chem. 274:11727-11735(1999).
//
RX   PubMed=22375833; DOI=10.1186/1471-2180-12-S1-S11; PMCID=PMC3287508;
RA   Pinto S.B., Mariconti M., Bazzocchi C., Bandi C., Sinkins S.P.;
RT   "Wolbachia surface protein induces innate immune responses in mosquito
RT   cells.";
RL   BMC Microbiol. 12 Suppl. 1:S11.1-S11.6(2012).
//
RX   PubMed=23382679; DOI=10.1371/journal.ppat.1003145; PMCID=PMC3561300;
RA   Lombardo F., Ghani Y., Kafatos F.C., Christophides G.K.;
RT   "Comprehensive genetic dissection of the hemocyte immune response in
RT   the malaria mosquito Anopheles gambiae.";
RL   PLoS Pathog. 9:e1003145.1-e1003145.11(2013).
//
RX   PubMed=36514125; DOI=10.1186/s13071-022-05590-3; PMCID=PMC9749150;
RA   Eggleston H., Njoya K., Anderson C.E., Holm I., Eiglmeier K.,
RA   Liang J.-T., Sharakhov I.V., Vernick K.D., Riehle M.M.;
RT   "Molecular characterization and genetic authentication assay for
RT   Anopheles 'hemocyte-like' cell lines 4a-3A and 4a-3B.";
RL   Parasit. Vectors 15:465.1-465.13(2022).
//