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Cellosaurus IOSE4CMYC (CVCL_YZ56)

[Text version]
Cell line name IOSE4CMYC
Synonyms iOSE4CMYC; IOE4CMYC
Accession CVCL_YZ56
Resource Identification Initiative To cite this cell line use: IOSE4CMYC (RRID:CVCL_YZ56)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:7553; MYC.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; B.cereus Bsr.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: In situ; Ovary, surface epithelium; UBERON=UBERON_0001304.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0T70 (IOSE4)
Sex of cell Female
Age at sampling Age unspecified
Category Telomerase immortalized cell line
Publications

PubMed=20360942; DOI=10.1593/neo.91948; PMCID=PMC2847739
Lawrenson K., Grun B., Benjamin E., Jacobs I.J., Dafou D., Gayther S.A.
Senescent fibroblasts promote neoplastic transformation of partially transformed ovarian epithelial cells in a three-dimensional model of early stage ovarian cancer.
Neoplasia 12:317-325(2010)

PubMed=30487138; DOI=10.1158/0008-5472.CAN-17-3864; PMCID=PMC6359979
Buckley M.A., Woods N.T., Tyrer J.P., Mendoza-Fandino G., Lawrenson K., Hazelett D.J., Najafabadi H.S., Gjyshi A., Carvalho R.S., Lyra P.C. Jr., Coetzee S.G., Shen H.C., Yang A.W., Earp M.A., Yoder S.J., Risch H., Chenevix-Trench G., Ramus S.J., Phelan C.M., Coetzee G.A., Noushmehr H., Hughes T.R., Sellers T.A., Goode E.L., Pharoah P.D.P., Gayther S.A., Monteiro A.N.A.
Functional analysis and fine mapping of the 9p22.2 ovarian cancer susceptibility locus.
Cancer Res. 79:467-481(2019)

Cross-references
Encyclopedic resources Wikidata; Q98126784
Entry history
Entry creation02-Jul-2020
Last entry update10-Apr-2025
Version number11