ID   IOSE4CMYC
AC   CVCL_YZ56
SY   iOSE4CMYC; IOE4CMYC
DR   Wikidata; Q98126784
RX   PubMed=20360942;
RX   PubMed=30487138;
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:7553; MYC.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; B.cereus Bsr.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Derived from site: In situ; Ovary, surface epithelium; UBERON=UBERON_0001304.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0T70 ! IOSE4
SX   Female
AG   Age unspecified
CA   Telomerase immortalized cell line
DT   Created: 02-07-20; Last updated: 10-04-25; Version: 11
//
RX   PubMed=20360942; DOI=10.1593/neo.91948; PMCID=PMC2847739;
RA   Lawrenson K., Grun B., Benjamin E., Jacobs I.J., Dafou D.,
RA   Gayther S.A.;
RT   "Senescent fibroblasts promote neoplastic transformation of partially
RT   transformed ovarian epithelial cells in a three-dimensional model of
RT   early stage ovarian cancer.";
RL   Neoplasia 12:317-325(2010).
//
RX   PubMed=30487138; DOI=10.1158/0008-5472.CAN-17-3864; PMCID=PMC6359979;
RA   Buckley M.A., Woods N.T., Tyrer J.P., Mendoza-Fandino G.,
RA   Lawrenson K., Hazelett D.J., Najafabadi H.S., Gjyshi A.,
RA   Carvalho R.S., Lyra P.C. Jr., Coetzee S.G., Shen H.C., Yang A.W.,
RA   Earp M.A., Yoder S.J., Risch H., Chenevix-Trench G., Ramus S.J.,
RA   Phelan C.M., Coetzee G.A., Noushmehr H., Hughes T.R., Sellers T.A.,
RA   Goode E.L., Pharoah P.D.P., Gayther S.A., Monteiro A.N.A.;
RT   "Functional analysis and fine mapping of the 9p22.2 ovarian cancer
RT   susceptibility locus.";
RL   Cancer Res. 79:467-481(2019).
//