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Cellosaurus MDCK.STAT1 KO (CVCL_YZ44)

[Text version]

Cell line name MDCK.STAT1 KO
Accession CVCL_YZ44
Resource Identification Initiative To cite this cell line use: MDCK.STAT1 KO (RRID:CVCL_YZ44)
Comments Group: Vaccine production cell line.
Characteristics: Excellent cell model for virus propagation and viral vaccine production. It exhibits significant increased viral titer and enhanced virus production capability when compared to its parental cell line (ATCC).
Doubling time: ~22 hours (ATCC).
Knockout cell: Method=CRISPR/Cas9; VGNC; -; STAT1.
Derived from sampling site: Kidney.
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Cocker Spaniel.
Hierarchy Parent: CVCL_0422 (MDCK)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line

Turner-Gillies E., Shapiro B.A., Tian F.
Generation of cell lines capable of producing high-titer viral stocks for use in vaccine manufacture and gene therapy.
(In) ATCC application note AP-082021-v01; pp.1-8; ATCC; Manassas (2021)

Cell line collections ATCC; CCL-34-VHG
Encyclopedic resources Wikidata; Q98127201
Entry history
Entry creation02-Jul-2020
Last entry update16-Dec-2021
Version number4