Cellosaurus cell line PK15 PERV-inactivated clone 15 (CVCL

Cross-references
Cell line name	PK15 PERV-inactivated clone 15
Synonyms	PK15 clone 15; PK15-15
Accession	CVCL_YE75
Resource Identification Initiative	To cite this cell line use: PK15 PERV-inactivated clone 15 (RRID:CVCL_YE75)
Comments	Characteristics: Using CRISPR/Cas9 all 62 copies of the PERV pol gene were inactivated (PubMed=26456528). Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Species of origin	Sus scrofa (Pig) (NCBI Taxonomy: 9823) Breed/subspecies: Hampshire; VBO=VBO_0001146.
Hierarchy	Parent: CVCL_2160 (PK-15)
Sex of cell	Male
Age at sampling	Adult
Category	Spontaneously immortalized cell line
Publications	PubMed=26456528; DOI=10.1126/science.aad1191 Lu-Han Yang, Marc Guell, Dong Niu, Haydy George, Emal Lesha, Dennis Grishin, John Aach, Ellen Shrock, Wei-Hong Xu, Jurgen Poci, Rebeca Cortazio ...Show all 14 authors... , Robert A. Wilkinson, Jay A. Fishman, George McDonald Church; Show fewer authors Genome-wide inactivation of porcine endogenous retroviruses (PERVs). Science 350:1101-1104(2015) PubMed=31667881; DOI=10.1111/xen.12563 Antonia W. Godehardt, Nicole Fischer, Paula Rauch, Barbara Gulich, Klaus Boller, George McDonald Church, Ralf Reinhard Tonjes; Characterization of porcine endogenous retrovirus particles released by the CRISPR/Cas9 inactivated cell line PK15 clone 15. Xenotransplantation 27:e12563.1-e12563.12(2020)
Encyclopedic resources	Wikidata; Q98128600
Entry history
Entry creation	19-Dec-2019
Last entry update	10-Sep-2024
Version number	5