• Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (PubMed=24735930).
  

PubMed=24735930; DOI=10.1186/1476-4598-13-83; PMCID=PMC4021505
Lassen A., Atefi M., Robert L., Wong D.J.L., Cerniglia M., Comin-Anduix B., Ribas A.
Effects of AKT inhibitor therapy in response and resistance to BRAF inhibition in melanoma.
Mol. Cancer 13:83.1-83.14(2014)

PubMed=29229836; DOI=10.1073/pnas.1712064115; PMCID=PMC5748184
Su Y.-P., Wei W., Robert L., Xue M., Tsoi J., Garcia-Diaz A., Homet Moreno B., Kim J., Ng R.H.-Y., Lee J.W., Koya R.C., Comin-Anduix B., Graeber T.G., Ribas A., Heath J.R.
Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance.
Proc. Natl. Acad. Sci. U.S.A. 114:13679-13684(2017)

PubMed=32393797; DOI=10.1038/s41467-020-15956-9; PMCID=PMC7214418
Su Y.-P., Ko M.E., Cheng H.-J., Zhu R.-H., Xue M., Wang J.K., Lee J.W., Frankiw L., Xu A., Wong S., Robert L., Takata K., Yuan D., Lu Y., Huang S., Ribas A., Levine R.D., Nolan G.P., Wei W., Plevritis S.K., Li G.-D., Baltimore D., Heath J.R.
Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line.
Nat. Commun. 11:2345.1-2345.12(2020)