Cellosaurus cell line M397-AR (CVCL

Cross-references
Cell line name	M397-AR
Synonyms	M397AR
Accession	CVCL_XK13
Resource Identification Initiative	To cite this cell line use: M397-AR (RRID:CVCL_XK13)
Comments	Selected for resistance to: ChEBI; CHEBI_63637; Vemurafenib (Zelboraf; PLX4032).
Sequence variations	Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (PubMed=24735930).
Disease	Melanoma (NCIt: C3224)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_XK00 (M397)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=24735930; DOI=10.1186/1476-4598-13-83; PMCID=PMC4021505 Amanda Lassen, Mohammad Atefi, Lidia Robert, Deborah Jean Lee Wong, Michael Cerniglia, Begonya Comin-Anduix, Antoni Ribas; Effects of AKT inhibitor therapy in response and resistance to BRAF inhibition in melanoma. Mol. Cancer 13:83.1-83.14(2014)
Cell line databases/resources	cancercelllines; CVCL_XK13
Encyclopedic resources	Wikidata; Q95984253
Entry history
Entry creation	19-Dec-2019
Last entry update	19-Dec-2024
Version number	7