Cellosaurus logo
expasy logo

Cellosaurus CH1-cisR (CVCL_X012)

[Text version]
Cell line name CH1-cisR
Synonyms CH1/cisR; CH1cisR; CH1Cis
Accession CVCL_X012
Resource Identification Initiative To cite this cell line use: CH1-cisR (RRID:CVCL_X012)
Comments Problematic cell line: Contaminated. Parent cell line (CH1) has been shown to be a PA-1 derivative.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00559.
Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Omics: Transcriptome analysis by microarray.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Heterozygous (from parent cell line).
Disease Ovarian mixed germ cell tumor (NCIt: C8114)
Mixed germ cell tumor (ORDO: Orphanet_180234)
Derived from metastatic site: Ascites.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4992 (CH1 [Human ovarian carcinoma])
Sex of cell Female
Age at sampling 12Y
Category Cancer cell line
STR profile Source(s): PubMed=11416159

Markers:
AmelogeninX
D8S117914,15
D18S5115,18
D21S1129,31.2
FGA24
TH017,9
vWA15,17

Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
Publications

PubMed=1617660
Kelland L.R., Mistry P., Abel G., Loh S.Y., O'Neill C.F., Murrer B.A., Harrap K.R.
Mechanism-related circumvention of acquired cis-diamminedichloroplatinum(II) resistance using two pairs of human ovarian carcinoma cell lines by ammine/amine platinum(IV) dicarboxylates.
Cancer Res. 52:3857-3864(1992)

Cross-references
Encyclopedic resources Wikidata; Q54811611
Gene expression databases GEO; GSM851915
Entry history
Entry creation17-Jul-2014
Last entry update21-Mar-2023
Version number18