ID   CH1-cisR
AC   CVCL_X012
SY   CH1/cisR; CH1cisR; CH1Cis
DR   cancercelllines; CVCL_X012
DR   GEO; GSM851915
DR   Wikidata; Q54811611
RX   PubMed=1617660;
RX   PubMed=11416159;
CC   Problematic cell line: Contaminated. Parent cell line (CH1) has been shown to be a PA-1 derivative.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00559.
CC   Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Heterozygous (from parent cell line).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
ST   Source(s): PubMed=11416159
ST   Amelogenin: X
ST   D18S51: 15,18
ST   D21S11: 29,31.2
ST   D8S1179: 14,15
ST   FGA: 24
ST   TH01: 7,9
ST   vWA: 15,17
DI   NCIt; C8114; Ovarian mixed germ cell tumor
DI   ORDO; Orphanet_180234; Mixed germ cell tumor
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_4992 ! CH1 [Human ovarian carcinoma]
SX   Female
AG   12Y
CA   Cancer cell line
DT   Created: 17-07-14; Last updated: 02-05-24; Version: 21
RX   PubMed=1617660;
RA   Kelland L.R., Mistry P., Abel G., Loh S.Y., O'Neill C.F., Murrer B.A.,
RA   Harrap K.R.;
RT   "Mechanism-related circumvention of acquired
RT   cis-diamminedichloroplatinum(II) resistance using two pairs of human
RT   ovarian carcinoma cell lines by ammine/amine platinum(IV)
RT   dicarboxylates.";
RL   Cancer Res. 52:3857-3864(1992).
RX   PubMed=11416159; DOI=10.1073/pnas.121616198;
RA   Masters J.R.W., Thomson J.A., Daly-Burns B., Reid Y.A., Dirks W.G.,
RA   Packer P., Toji L.H., Ohno T., Tanabe H., Arlett C.F., Kelland L.R.,
RA   Harrison M., Virmani A.K., Ward T.H., Ayres K.L., Debenham P.G.;
RT   "Short tandem repeat profiling provides an international reference
RT   standard for human cell lines.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001).