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Cellosaurus SBC-2 [Human SCLC] (CVCL_W531)

[Text version]
Cell line name SBC-2 [Human SCLC]
Accession CVCL_W531
Resource Identification Initiative To cite this cell line use: SBC-2 [Human SCLC] (RRID:CVCL_W531)
Comments Problematic cell line: Possibly misidentified/contaminated. Shown to be identical to SBC-1 (JCRB web site and STR profile).
Population: Japanese.
Doubling time: 33.8 hours (PubMed=8286010).
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_1676 ! SBC-1
Sex of cell Male
Age at sampling 46Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB0817

Markers:
AmelogeninX
CSF1PO10,12
D5S8189,11
D7S82011,12
D13S31712
D16S5399
TH018,9
TPOX8
vWA14,17

Run an STR similarity search on this cell line
Publications

CLPUB00132
Nobuyasu Kishimoto, Taisuke Ohnoshi, Shunkichi Hiraki, Kenishi Miyake, Shiro Ozawa, Tetsuo Tamura, Takeyuki Numata, Shin Kawahara, Ryo Tamura, Hiroaki Miyamoto, Kenji Nishii, Ikuro Kimura;
Establishment and characterization of five cell lines from human small cell carcinoma of the lung.
Nihon Haigan Gakkai 24:644-644(1984)

DOI=10.4044/joma1947.104.9-10_905
Nobuyasu Kishimoto;
Studies on cell biology and chemotherapy of lung cancer using tissue culture techniques. Part 2. Biological characteristics of five newly established small cell lung cancer cell lines.
Okayama Igakkai Zasshi 104:905-913(1992)

PubMed=8286010
Katsuyuki Kiura, Shinobu Watarai, Takuo Shibayama, Taisuke Ohnoshi, Ikuro Kimura, Tatsuji Yasuda;
Inhibitory effects of cholera toxin on in vitro growth of human lung cancer cell lines.
Anticancer Drug Des. 8:417-428(1993)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Li-Qun Jia, Motonobu Osada, Chikashi Ishioka, Makio Gamo, Shuntaro Ikawa, Takao Suzuki, Hideki Shimodaira, Tomohito Niitani, Toshio Kudo, Mitoshi Akiyama, Narimiti Kimura ...Show all 18 authors... , Mitsuyoshi Matsuo, Hiroshi Mizusawa, Noriho Tanaka, Hideki Koyama, Masayoshi Namba, Ryunosuke Kanamaru, Toshio Kuroki; Show fewer authors
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=9413215
Hiromishi Yamane, Katsuyuki Kiura, Masahiro Tabata, Akihiro Bessho, Tadashi Tsuchida, Kinya Motoda, Akio Hiraki, Hiroshi Ueoka, Mine Harada;
Small cell lung cancer can express CD34 antigen.
Anticancer Res. 17:3627-3632(1997)

PubMed=10358721; DOI=10.18926/AMO/31626
Akio Matsushita, Masahiro Tabata, Hiroshi Ueoka, Katsuyuki Kiura, Takuo Shibayama, Keisuke Aoe, Hiroyuki Kohara, Mine Harada;
Establishment of a drug sensitivity panel using human lung cancer cell lines.
Acta Med. Okayama 53:67-75(1999)

PubMed=10628341
Shigeki Ikubo, Nagio Takigawa, Hiroshi Ueoka, Katsuyuki Kiura, Masahiro Tabata, Takuo Shibayama, Masakazu Chikamori, Keisuke Aoe, Akio Matsushita, Mine Harada;
In vitro evaluation of antimicrotubule agents in human small-cell lung cancer cell lines.
Anticancer Res. 19:3985-3988(1999)

PubMed=15016488; DOI=10.1016/S0140-6736(04)15693-6
Michael H. Jones, Carl Virtanen, Daisuke Honjoh, Tatsu Miyoshi, Yukitoshi Satoh, Sakae Okumura, Ken Nakagawa, Hitoshi Nomura, Yuichi Ishikawa;
Two prognostically significant subtypes of high-grade lung neuroendocrine tumours independent of small-cell and large-cell neuroendocrine carcinomas identified by gene expression profiles.
Lancet 363:775-781(2004)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
S. Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera ...Show all 22 authors... , Rui Wang, Angela Tam, Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=22399608
Tadashi Tsuchida, Hiromishi Yamane, Nobuaki Ochi, Takayuki Tabayashi, Akio Hiraki, Naoyuki Nogami, Nagio Takigawa, Katsuyuki Kiura, Mitsune Tanimoto;
Cytotoxicity of activated natural killer cells and expression of adhesion molecules in small-cell lung cancer.
Anticancer Res. 32:887-892(2012)

Cross-references
Cell line collections (Providers) JCRB; JCRB0817
Cell line databases/resources CLO; CLO_0008951
cancercelllines; CVCL_W531
Cell_Model_Passport; SIDM00366
LINCS_LDP; LCL-1866
Encyclopedic resources Wikidata; Q54952165
Gene expression databases GEO; GSM17312
GEO; GSM827568
Polymorphism and mutation databases Progenetix; CVCL_W531
Entry history
Entry creation16-Apr-2014
Last entry update10-Apr-2025
Version number23