| Cell line name |
EIIL |
| Accession |
CVCL_W441 |
| Resource Identification Initiative |
To cite this cell line use: EIIL (RRID:CVCL_W441) |
| Comments |
Population: Japanese. Characteristics: Estrogen-independent (PubMed=7699285). Derived from site: In situ; Endometrium; UBERON=UBERON_0001295. |
| Sequence variations |
- Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Leu570Pro (c.1709T>C); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9177; POLE; Simple; p.Pro102Ser (c.304C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9177; POLE; Simple; p.Asn751fs (c.2252delA); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Glu288fs*3 (c.863delA); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Thr319fs*1 (c.950_953delTACT) (p.VL317fs) (V317fs*3); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Asp49His (c.145G>C); ClinVar=VCV000135948; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met246Val (c.736A>G); ClinVar=VCV000100815; Zygosity=Heterozygous (from parent cell line).
|
| Disease |
Type I endometrial adenocarcinoma (NCIt: C40145) |
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
| Hierarchy |
Parent: CVCL_2529 (Ishikawa) |
| Sex of cell |
Female |
| Age at sampling |
39Y |
| Category |
Cancer cell line |
| Publications | PubMed=7699285 Hideki Sakamoto, Xiao-Hong Deng, Takashi Shirakawa, Sachiko Ige, Kaori Ohtani, Ayako Saitoh, Masashi Takami, Takeshi Takami, Kazuo Satoh; Establishment of metastatic sub-clone from estrogen independent Ishikawa cells and its characterization in vitro and in vivo. Nihon Sanka Fujinka Gakkai Zasshi 47:249-256(1995) PubMed=8718550 Takashi Shirakawa, Hideki Sakamoto, Kazuo Satoh; Separation and characterization of estrogen independent endometrial cancer cell line originated from Ishikawa strain. Nihon Sanka Fujinka Gakkai Zasshi 48:139-146(1996) PubMed=10381137; DOI=10.1016/S0304-3835(98)00270-5 Hiroho Ohta, Hideki Sakamoto, Kazuo Satoh; In vitro effects of gonadotropin-releasing hormone (GnRH) analogue on cancer cell sensitivity to cis-platinum. Cancer Lett. 134:111-118(1998) |
| Cross-references |
| Cell line databases/resources |
cancercelllines; CVCL_W441
|
| Encyclopedic resources |
Wikidata; Q54832166
|
| Entry history |
| Entry creation | 16-Apr-2014 |
| Last entry update | 19-Dec-2024 |
| Version number | 11 |
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