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Cellosaurus EIIL (CVCL_W441)

[Text version]

Cell line name EIIL
Accession CVCL_W441
Resource Identification Initiative To cite this cell line use: EIIL (RRID:CVCL_W441)
Comments Population: Japanese.
Derived from sampling site: Endometrium.
Sequence variations
  • Mutation; HGNC; 8979; PIK3R1; Simple; p.Leu570Pro (c.1709T>C); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9177; POLE; Simple; p.Pro102Ser (c.304C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9177; POLE; Simple; p.Asn751fs (c.2252delA); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Glu288fs*3 (c.863delA); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Thr319fs*1 (c.950_953delTACT) (p.VL317fs) (V317fs*3); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Asp49His (c.145G>C); ClinVar=VCV000135948; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Met246Val (c.736A>G); ClinVar=VCV000100815; Zygosity=Heterozygous (from parent cell line).
Disease Endometrial adenocarcinoma (NCIt: C7359)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2529 (Ishikawa)
Sex of cell Female
Age at sampling 39Y
Category Cancer cell line
Publications

PubMed=7699285
Sakamoto H., Deng X., Shirakawa T., Ige S., Ohtani K., Saitoh A., Takami M., Takami T., Satoh K.
Establishment of metastatic sub-clone from estrogen independent Ishikawa cells and its characterization in vitro and in vivo.
Nihon Sanka Fujinka Gakkai Zasshi 47:249-256(1995)

PubMed=8718550
Shirakawa T., Sakamoto H., Satoh K.
Separation and characterization of estrogen independent endometrial cancer cell line originated from Ishikawa strain.
Nihon Sanka Fujinka Gakkai Zasshi 48:139-146(1996)

Cross-references
Encyclopedic resources Wikidata; Q54832166
Entry history
Entry creation16-Apr-2014
Last entry update16-Dec-2021
Version number7