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Cellosaurus Panc-1-CTC (CVCL_VQ69)

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Cell line name Panc-1-CTC
Synonyms Panc-1-Circulating Tumor Cells
Accession CVCL_VQ69
Resource Identification Initiative To cite this cell line use: Panc-1-CTC (RRID:CVCL_VQ69)
Comments Population: Caucasian.
Characteristics: Exhibits more profound migratory and invasive abilities than the parent cell line in vitro. Has a higher tumor-forming ability than the parent cell line in vivo.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0480 (PANC-1)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=30156359; DOI=10.1111/cas.13783; PMCID=PMC6215881
Taku Sato, Tomoki Muramatsu, Minoru Tanabe, Johji Inazawa;
Identification and characterization of transforming growth factor beta induced in circulating tumor cell subline from pancreatic cancer cell line.
Cancer Sci. 109:3623-3633(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_VQ69
Encyclopedic resources Wikidata; Q98128480
Gene expression databases GEO; GSM3333106
GEO; GSM3333107
GEO; GSM3333110
GEO; GSM3333111
Entry history
Entry creation13-Nov-2018
Last entry update10-Apr-2025
Version number11