ID   Panc-1-CTC
AC   CVCL_VQ69
SY   Panc-1-Circulating Tumor Cells
DR   cancercelllines; CVCL_VQ69
DR   GEO; GSM3333106
DR   GEO; GSM3333107
DR   GEO; GSM3333110
DR   GEO; GSM3333111
DR   Wikidata; Q98128480
RX   PubMed=30156359;
CC   Population: Caucasian.
CC   Characteristics: Exhibits more profound migratory and invasive abilities than the parent cell line in vitro. Has a higher tumor-forming ability than the parent cell line in vivo.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
DI   NCIt; C9120; Pancreatic ductal adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0480 ! PANC-1
SX   Male
AG   56Y
CA   Cancer cell line
DT   Created: 13-11-18; Last updated: 10-04-25; Version: 11
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RX   PubMed=30156359; DOI=10.1111/cas.13783; PMCID=PMC6215881;
RA   Sato T., Muramatsu T., Tanabe M., Inazawa J.;
RT   "Identification and characterization of transforming growth factor
RT   beta induced in circulating tumor cell subline from pancreatic cancer
RT   cell line.";
RL   Cancer Sci. 109:3623-3633(2018).
//