Cell line name |
UM-UC-3-LuL-1 |
Synonyms |
LuL-1; Luciferase Lung metastasis-1 |
Accession |
CVCL_VL57 |
Resource Identification Initiative |
To cite this cell line use: UM-UC-3-LuL-1 (RRID:CVCL_VL57) |
Comments |
Population: Caucasian. Characteristics: Produced after passage of UM-UC-3-Luc into nude mice. Transfected with: UniProtKB; P08659; Firefly luciferase. Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR). Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255. |
Sequence variations |
- Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
- Gene deletion; HGNC; 9588; PTEN; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 795; ATM; Simple; p.Gln2800fs*6 (c.8400delG); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 14446; PARD3B; Unexplicit; Ex9-18del; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Phe113Cys (c.338T>G); ClinVar=VCV000634690; Zygosity=Homozygous (from parent cell line).
|
Disease |
Bladder carcinoma (NCIt: C4912) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_VL56 (UM-UC-3-Luc) Children:
|
Sex of cell |
Male |
Age at sampling |
Age unspecified |
Category |
Cancer cell line |
Publications | PubMed=21482678; DOI=10.1158/0008-5472.CAN-11-0519 Overdevest J.B., Thomas S., Kristiansen G., Hansel D.E., Smith S.C., Theodorescu D. CD24 offers a therapeutic target for control of bladder cancer metastasis based on a requirement for lung colonization. Cancer Res. 71:3802-3811(2011) PubMed=29732388; DOI=10.3233/BLC-180167 Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D. Systematic review: characteristics and preclinical uses of bladder cancer cell lines. Bladder Cancer 4:169-183(2018) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_VL57
|
Encyclopedic resources |
Wikidata; Q98134083
|
Entry history |
Entry creation | 07-Sep-2018 |
Last entry update | 05-Oct-2023 |
Version number | 10 |
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