Cellosaurus cell line UM-UC-3-Luc (CVCL

Cellosaurus UM-UC-3-Luc (CVCL_VL56)

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Cell line name

UM-UC-3-Luc

Accession

CVCL_VL56

Resource Identification Initiative

To cite this cell line use: UM-UC-3-Luc (RRID:CVCL_VL56)

Comments

Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.

Sequence variations

Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
Gene deletion; HGNC; HGNC:9588; PTEN; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; HGNC:795; ATM; Simple; p.Gln2800fs*6 (c.8400delG); Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; HGNC:14446; PARD3B; Unexplicit; Ex9-18del; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Phe113Cys (c.338T>G); ClinVar=VCV000634690; Zygosity=Unspecified (from parent cell line).

Disease

Bladder carcinoma (NCIt: C4912)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_1783 (UM-UC-3)
Children:

CVCL_VL57 (UM-UC-3-LuL-1)

Sex of cell

Male

Age at sampling

Age unspecified