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Cellosaurus UM-UC-3-Luc (CVCL_VL56)

[Text version]
Cell line name UM-UC-3-Luc
Accession CVCL_VL56
Resource Identification Initiative To cite this cell line use: UM-UC-3-Luc (RRID:CVCL_VL56)
Comments Population: Caucasian.
Transfected with: UniProtKB; P08659; Firefly luciferase.
Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Gene deletion; HGNC; 9588; PTEN; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 795; ATM; Simple; p.Gln2800fs*6 (c.8400delG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 14446; PARD3B; Unexplicit; Ex9-18del; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Phe113Cys (c.338T>G); ClinVar=VCV000634690; Zygosity=Unspecified (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1783 (UM-UC-3)
Children:
CVCL_VL57 (UM-UC-3-LuL-1)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=21482678; DOI=10.1158/0008-5472.CAN-11-0519
Overdevest J.B., Thomas S., Kristiansen G., Hansel D.E., Smith S.C., Theodorescu D.
CD24 offers a therapeutic target for control of bladder cancer metastasis based on a requirement for lung colonization.
Cancer Res. 71:3802-3811(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_VL56
Encyclopedic resources Wikidata; Q98134081
Entry history
Entry creation07-Sep-2018
Last entry update05-Oct-2023
Version number10