ID   UM-UC-3-Luc
AC   CVCL_VL56
DR   cancercelllines; CVCL_VL56
DR   Wikidata; Q98134081
RX   PubMed=21482678;
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Gene deletion; HGNC; 9588; PTEN; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 795; ATM; Simple; p.Gln2800fs*6 (c.8400delG); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 14446; PARD3B; Unexplicit; Ex9-18del; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Phe113Cys (c.338T>G); ClinVar=VCV000634690; Zygosity=Unspecified (from parent cell line).
CC   Transfected with: UniProtKB; P08659; Firefly luciferase.
CC   Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
DI   NCIt; C4912; Bladder carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1783 ! UM-UC-3
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 07-09-18; Last updated: 05-10-23; Version: 10
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RX   PubMed=21482678; DOI=10.1158/0008-5472.CAN-11-0519;
RA   Overdevest J.B., Thomas S., Kristiansen G., Hansel D.E., Smith S.C.,
RA   Theodorescu D.;
RT   "CD24 offers a therapeutic target for control of bladder cancer
RT   metastasis based on a requirement for lung colonization.";
RL   Cancer Res. 71:3802-3811(2011).
//