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Cellosaurus AT4BI (CVCL_V546)

[Text version]
Cell line name AT4BI
Synonyms Ataxia Telangiectasia 4 BIrmingham
Accession CVCL_V546
Resource Identification Initiative To cite this cell line use: AT4BI (RRID:CVCL_V546)
Comments Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Disease Ataxia telangiectasia syndrome (NCIt: C2887)
Ataxia telangiectasia (ORDO: Orphanet_100)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_4Y28 (AT4BI(SV))CVCL_C1HJ (AT4BINE1-3)
Sex of cell Male
Age at sampling 6Y
Category Finite cell line
Publications

PubMed=1196376; DOI=10.1038/258427a0
Taylor A.M.R., Harnden D.G., Arlett C.F., Harcourt S.A., Lehmann A.R., Stevens S., Bridges B.A.
Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity.
Nature 258:427-429(1975)

PubMed=837385
Lehmann A.R., Kirk-Bell S., Arlett C.F., Harcourt S.A., de Weerd-Kastelein E.A., Keijzer W., Hall-Smith P.
Repair of ultraviolet light damage in a variety of human fibroblast cell strains.
Cancer Res. 37:904-910(1977)

PubMed=865488; DOI=10.1016/0027-5107(77)90138-5
Remsen J.F., Cerutti P.A.
Excision of gamma-ray induced thymine lesions by preparations from ataxia telangiectasia fibroblasts.
Mutat. Res. 43:139-145(1977)

PubMed=7471106
Arlett C.F., Harcourt S.A.
Survey of radiosensitivity in a variety of human cell strains.
Cancer Res. 40:926-932(1980)

PubMed=6810166; DOI=10.1016/0027-5107(82)90299-8
Barfknecht T.R., Little J.B.
Hypersensitivity of ataxia telangiectasia skin fibroblasts to DNA alkylating agents.
Mutat. Res. 94:369-382(1982)

DOI=10.1007/978-1-4757-1117-2_12
Arlett C.F., Harcourt S.A.
The mutagen sensitivity response of cells from individuals heterozygous for DNA repair deficiency genes.
(In) The use of human cells for the evaluation of risk from physical and chemical agents; Castellani A. (eds.); pp.155-167; Springer; Boston (1983)

PubMed=6876478; DOI=10.1007/BF01897042
Ikenaga M., Midorikawa M., Abe J., Mimaki T.
The sensitivities to radiations and radiomimetic chemicals of cells from patients with ataxia telangiectasia.
Jinrui Idengaku Zasshi 28:1-10(1983)

PubMed=2903889; DOI=10.1080/09553008814552321
Arlett C.F., Green M.H.L., Priestley A., Harcourt S.A., Mayne L.V.
Comparative human cellular radiosensitivity: I. The effect of SV40 transformation and immortalisation on the gamma-irradiation survival of skin derived fibroblasts from normal individuals and from ataxia-telangiectasia patients and heterozygotes.
Int. J. Radiat. Biol. 54:911-928(1988)

PubMed=2973075; DOI=10.2307/3577479
Fertil B., Deschavanne P.J., Debieu D., Malaise E.-P.
Correlation between PLD repair capacity and the survival curve of human fibroblasts in exponential growth phase: analysis in terms of several parameters.
Radiat. Res. 116:74-88(1988)

PubMed=3337113
Jaspers N.G.J., Taalman R.D.F.M., Baan C.C.
Patients with an inherited syndrome characterized by immunodeficiency, microcephaly, and chromosomal instability: genetic relationship to ataxia telangiectasia.
Am. J. Hum. Genet. 42:66-73(1988)

PubMed=9650596; DOI=10.2307/3579639
Enns L., Barley R.D.C., Paterson M.C., Mirzayans R.
Radiosensitivity in ataxia telangiectasia fibroblasts is not associated with deregulated apoptosis.
Radiat. Res. 150:11-16(1998)

PubMed=18079351; DOI=10.1259/bjr/27072321
Arlett C.F., Green M.H.L., Rogers P.B., Lehmann A.R., Plowman P.N.
Minimal ionizing radiation sensitivity in a large cohort of xeroderma pigmentosum fibroblasts.
Br. J. Radiol. 81:51-58(2008)

Cross-references
Cell line collections (Providers) JCRB; KURB1761
Encyclopedic resources Wikidata; Q54750928
Entry history
Entry creation16-Apr-2014
Last entry update29-Jun-2023
Version number13