Cellosaurus cell line AT4BINE1-3 (CVCL

Cross-references
Cell line name	AT4BINE1-3
Accession	CVCL_C1HJ
Resource Identification Initiative	To cite this cell line use: AT4BINE1-3 (RRID:CVCL_C1HJ)
Comments	Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen. Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Disease	Ataxia telangiectasia syndrome (NCIt: C2887) Ataxia telangiectasia (ORDO: Orphanet_100)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_V546 (AT4BI)
Sex of cell	Male
Age at sampling	6Y
Category	Transformed cell line
Publications	PubMed=2903889; DOI=10.1080/09553008814552321 Arlett C.F., Green M.H.L., Priestley A., Harcourt S.A., Mayne L.V. Comparative human cellular radiosensitivity: I. The effect of SV40 transformation and immortalisation on the gamma-irradiation survival of skin derived fibroblasts from normal individuals and from ataxia-telangiectasia patients and heterozygotes. Int. J. Radiat. Biol. 54:911-928(1988) PubMed=9357546; DOI=10.1016/S0027-5107(97)00119-x Sprung C.N., Bryan T.M., Reddel R.R., Murnane J.P. Normal telomere maintenance in immortal ataxia telangiectasia cell lines. Mutat. Res. 379:177-184(1997)
Encyclopedic resources	Wikidata; Q114310635
Entry history
Entry creation	22-Sep-2022
Last entry update	19-Dec-2024
Version number	6