ID   AT4BI
AC   CVCL_V546
SY   Ataxia Telangiectasia 4 BIrmingham
DR   JCRB; KURB1761
DR   Wikidata; Q54750928
RX   DOI=10.1007/978-1-4757-1117-2_12;
RX   PubMed=837385;
RX   PubMed=865488;
RX   PubMed=1196376;
RX   PubMed=2903889;
RX   PubMed=2973075;
RX   PubMed=3337113;
RX   PubMed=6810166;
RX   PubMed=6876478;
RX   PubMed=7471106;
RX   PubMed=9650596;
RX   PubMed=18079351;
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
DI   NCIt; C2887; Ataxia telangiectasia syndrome
DI   ORDO; Orphanet_100; Ataxia telangiectasia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   6Y
CA   Finite cell line
DT   Created: 16-04-14; Last updated: 29-06-23; Version: 13
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RX   DOI=10.1007/978-1-4757-1117-2_12;
RA   Arlett C.F., Harcourt S.A.;
RT   "The mutagen sensitivity response of cells from individuals
RT   heterozygous for DNA repair deficiency genes.";
RL   (In) The use of human cells for the evaluation of risk from physical and chemical agents; Castellani A. (eds.); pp.155-167; Springer; Boston (1983).
//
RX   PubMed=837385;
RA   Lehmann A.R., Kirk-Bell S., Arlett C.F., Harcourt S.A.,
RA   de Weerd-Kastelein E.A., Keijzer W., Hall-Smith P.;
RT   "Repair of ultraviolet light damage in a variety of human fibroblast
RT   cell strains.";
RL   Cancer Res. 37:904-910(1977).
//
RX   PubMed=865488; DOI=10.1016/0027-5107(77)90138-5;
RA   Remsen J.F., Cerutti P.A.;
RT   "Excision of gamma-ray induced thymine lesions by preparations from
RT   ataxia telangiectasia fibroblasts.";
RL   Mutat. Res. 43:139-145(1977).
//
RX   PubMed=1196376; DOI=10.1038/258427a0;
RA   Taylor A.M.R., Harnden D.G., Arlett C.F., Harcourt S.A., Lehmann A.R.,
RA   Stevens S., Bridges B.A.;
RT   "Ataxia telangiectasia: a human mutation with abnormal radiation
RT   sensitivity.";
RL   Nature 258:427-429(1975).
//
RX   PubMed=2903889; DOI=10.1080/09553008814552321;
RA   Arlett C.F., Green M.H.L., Priestley A., Harcourt S.A., Mayne L.V.;
RT   "Comparative human cellular radiosensitivity: I. The effect of SV40
RT   transformation and immortalisation on the gamma-irradiation survival
RT   of skin derived fibroblasts from normal individuals and from
RT   ataxia-telangiectasia patients and heterozygotes.";
RL   Int. J. Radiat. Biol. 54:911-928(1988).
//
RX   PubMed=2973075; DOI=10.2307/3577479;
RA   Fertil B., Deschavanne P.J., Debieu D., Malaise E.-P.;
RT   "Correlation between PLD repair capacity and the survival curve of
RT   human fibroblasts in exponential growth phase: analysis in terms of
RT   several parameters.";
RL   Radiat. Res. 116:74-88(1988).
//
RX   PubMed=3337113;
RA   Jaspers N.G.J., Taalman R.D.F.M., Baan C.C.;
RT   "Patients with an inherited syndrome characterized by
RT   immunodeficiency, microcephaly, and chromosomal instability: genetic
RT   relationship to ataxia telangiectasia.";
RL   Am. J. Hum. Genet. 42:66-73(1988).
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RX   PubMed=6810166; DOI=10.1016/0027-5107(82)90299-8;
RA   Barfknecht T.R., Little J.B.;
RT   "Hypersensitivity of ataxia telangiectasia skin fibroblasts to DNA
RT   alkylating agents.";
RL   Mutat. Res. 94:369-382(1982).
//
RX   PubMed=6876478; DOI=10.1007/BF01897042;
RA   Ikenaga M., Midorikawa M., Abe J., Mimaki T.;
RT   "The sensitivities to radiations and radiomimetic chemicals of cells
RT   from patients with ataxia telangiectasia.";
RL   Jinrui Idengaku Zasshi 28:1-10(1983).
//
RX   PubMed=7471106;
RA   Arlett C.F., Harcourt S.A.;
RT   "Survey of radiosensitivity in a variety of human cell strains.";
RL   Cancer Res. 40:926-932(1980).
//
RX   PubMed=9650596; DOI=10.2307/3579639;
RA   Enns L., Barley R.D.C., Paterson M.C., Mirzayans R.;
RT   "Radiosensitivity in ataxia telangiectasia fibroblasts is not
RT   associated with deregulated apoptosis.";
RL   Radiat. Res. 150:11-16(1998).
//
RX   PubMed=18079351; DOI=10.1259/bjr/27072321;
RA   Arlett C.F., Green M.H.L., Rogers P.B., Lehmann A.R., Plowman P.N.;
RT   "Minimal ionizing radiation sensitivity in a large cohort of xeroderma
RT   pigmentosum fibroblasts.";
RL   Br. J. Radiol. 81:51-58(2008).
//