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Cellosaurus Jurkat-111 (CVCL_U326)

[Text version]
Cell line name Jurkat-111
Synonyms Jurkat 111; J-111
Accession CVCL_U326
Resource Identification Initiative To cite this cell line use: Jurkat-111 (RRID:CVCL_U326)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8129.
Population: Caucasian.
Characteristics: Highly increased IL2 expression.
Transformant: NCIt; C17262; X-Ray.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Sequence variations
  • Mutation; HGNC; 959; BAX; Simple; p.Glu41Argfs*19 (c.121delG); ClinVar=VCV000009512; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 959; BAX; Simple; p.Glu41Glyfs*33 (c.121dupG); ClinVar=VCV000009511; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 16712; FBXW7; Simple; p.Arg505Cys (c.1513C>T); ClinVar=VCV000069961; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 6079; INPP5D; Simple; p.Gln345Ter (c.1033C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 6079; INPP5D; Simple; c.1097+1065_1097+1112del47; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 7325; MSH2; Simple; p.Arg711Ter (c.2131C>T); ClinVar=VCV000090903; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Heterozygous (from parent cell line).
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0065 (Jurkat)
Sex of cell Male
Age at sampling 14Y
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX
CSF1PO11
D5S8189
D7S8208,10,11
D13S3178,10,11
D16S53911,12
TH016,9.3
TPOX8,10
vWA18,19

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Publications

Patent=EP0142268A1
Taniguchi T., Matsui H., Hamuro J., Sato T., Sano K.
Saccharomyces cerevisiae possessing gene coding for interleukin-2 polypeptide and method for producing interleukin-2 using the yeast.
Patent number EP0142268A1, 22-May-1985

Patent=US5795777
Taniguchi T., Muramatsu M., Sugano H., Matsui H., Kashima N., Hamuro J.
Gene coded for interleukin-2 polypeptide, recombinant DNA carrying the said gene, a living cell line possessing the recombinant DNA, and method for producing interleukin-2 using the said cell.
Patent number US5795777, 18-Aug-1998

Cross-references
Cell line collections (Providers) ATCC; CRL-8129
Cell line databases/resources cancercelllines; CVCL_U326
Biological sample resources BioSample; SAMN03471193
Encyclopedic resources Wikidata; Q54899146
Entry history
Entry creation03-Feb-2014
Last entry update05-Oct-2023
Version number21